Now showing items 1-20 of 536

  • Molecular imaging of tau in the pathological cascade of Alzheimer’s disease 

    Chiotis, Konstantinos (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-11-10)
    The pathology of Alzheimer’s disease (AD) is characterised by the misfolding and aggregation of amyloid-β (Aβ) into extracellular plaques and aggregation of tau into intracellular neurofibrillary tangles. Recent advances ...
  • Technology use among older adults with and without cognitive impairment : exploring relations with daily life occupations and need of support 

    Ryd, Charlotta (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-11-06)
    Introduction: Older adults with and without cognitive impairments are likely to be limited in their performance of and engagement in daily life occupations due to challenges in everyday technology (ET) use. The ...
  • A continuing educational intervention in primary health care using the ConPrim model 

    Berggren, Erika (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-10-17)
    Background and aim: The overall aim of this thesis was to evaluate an intervention about “Nutritional care for patients cared for at home” developed using an interprofessional continuing educational model adapted for primary ...
  • Injuries, risk factors, consequences and injury perceptions in adolescent elite athletes 

    Rosen, Philip von (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-09-28)
    Background: Injury and health data are not fully explored in adolescent elite athletes, yet essential for understanding injury risk, consequences of injuries and developing injury preventive programs. Aims: To explore ...
  • Monitoring calls in telephone advice nursing : parents´and telenurses´experiences 

    Sandelius, Susanna (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-09-22)
    Background: Approximately 2 million of the 4.5 million calls made in 2016 to the 1177 healthcare advice line resulted in the telenurse providing self-care advice to the care seeker. In some of these calls, the care seekers ...
  • The matter of white and gray matter in cognitive impairment 

    Damangir, Soheil (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-08-03)
    Cognitive impairment spans from minor subjective cognitive impairment to disabling dementia. Many biomarkers have been developed to monitor different aspects of cognitive impairment. Magnetic resonance imaging is the ...
  • Inter-individual differences in associative memory : structural and functional brain correlates and genetic modulators 

    Becker, Nina (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-08-03)
    Our memory for personal experiences (e.g., the first day at school) is termed episodic memory. This form of memory involves the recollection of single information as well as the connection between these pieces of information ...
  • Specification and potency of human neural stem cells for clinical transplantation 

    Vincent, Per Henrik (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-24)
    Neural stem cells hold promise for future treatment of spinal cord injury. Various aspects regarding cell fate specification, manufacturing and monitoring, with implications for clinical applications of these cells, are ...
  • Primary care patients with common mental disorders : quality of life, sick leave and effects of group therapy 

    Ejeby, Kersti (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-19)
    Background: Depression, Anxiety and Stress-Related Disorders, Common Mental Disorders (CMDs) are common among patients in primary health care, with many left untreated or even undiagnosed. CMDs are associated with high ...
  • How well are we aging? : capturing the complexity of health trajectories of older adults 

    Santoni, Giola (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-12)
    Despite its positive nature, population aging represents a public health challenge that could be alleviated by maintaining good health during older age. The aim of this thesis was to evaluate how well people are aging, ...
  • Neuroimaging biomarkers in Alzheimer’s disease 

    Falahati Asrami, Farshad (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-11)
    Alzheimer’s disease (AD) is characterized by an accumulation of abnormal plaques and tangles in the brain, a process that is estimated to begin years before the appearance of clinical symptoms. Individuals with subjective ...
  • Depression & cognition in the elderly : neuroimaging perspective 

    Lebedeva, Aleksandra (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-05-03)
    This thesis examines the relationship between depression and brain structure in the elderly with (Study I, III) and without (Study II, IV) cognitive impairment (Alzheimer’s disease and mild cognitive impairment). Individuals ...
  • Lifestyle, cognitive aging, and brain correlates 

    Köhncke, Ylva (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-04-28)
    Inter-individual differences in level and rate of cognitive decline typically seen in aging have been linked to inter-individual differences in lifestyle factors such as leisure activities, including physical activity. The ...
  • The influence of sex hormones on neuromuscular function and premenstrual symptoms 

    Ekenros, Linda (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-04-13)
    The menstrual cycle with fluctuation in female sex hormones has been suggested to influence neuromuscular function. However, variation in ligament laxity, soft tissue stiffness, and skeletal muscle strength across the ...
  • Vårdskador vid omvårdnad : en studie av patienters, anhörigas och vårdgivares anmälningar 

    Andersson, Åsa (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-23)
    Background: Patient safety has, over the last decades, been increasingly established as an important global issue. Patient safety is jeopardized by for example adverse events and most of the current evidence on adverse ...
  • Elderly patients undergoing colorectal cancer surgery : can care be further improved? 

    Schubert Samuelsson, Katja (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-17)
    Introduction: Colorectal cancer (CRC) is one of the most common malignancies affecting approximately 6 400 new patients/year in Sweden of which 44% are 75 years and older at diagnosis. In order to identify potential ...
  • Genetic and lifestyle influences on memory, brain structure, and dementia 

    Ferencz, Beata (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-16)
    This doctoral thesis investigated genetic, inflammatory, and lifestyle influences on cognition, brain structure, and dementia. The influence of TOMM40 polymorphisms (Study I), a PICALM, BIN1 and CLU genetic risk score ...
  • Apolipoprotein E and cholinergic enzymes : the interface in dementia 

    Vijayaraghavan, Swetha (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-10)
    The main confirmed genetic risk factor for sporadic form of Alzheimer’s disease (AD) is apolipoprotein E (ApoE) ε4 allele (APOE4). ApoE protein aids in receptor ligand mediated transport, distribution and metabolism of ...
  • Falls in wheelchair users with spinal cord injury : incidence, risks and concerns 

    Butler Forslund, Emelie (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-02)
    Background: Knowledge about falls and related injuries in persons with spinal cord injuries (SCI) is limited, especially concerning wheelchair users. Further research is required in order to develop future prevention ...
  • Meaning-making in integrative health care : studies on patients’ and practitioners’ experiences 

    Andermo, Susanne (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-01)
    Background and aim: Patients living with chronic pain often turn both to conventional and complementary health care. Integrative health care combines conventional and complementary therapies in the clinical care of ...