Publications from KI: Recent submissions
Now showing items 61-80 of 10113
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Prolonged immobilization compromises up-regulation of repair genes after tendon rupture in a rat model
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-03)It was hypothesized that mobilization versus immobilization after injury would promote tissue healing by regulating gene expression for molecules associated with repair. Cast immobilization versus free mobilization was ... -
High plantar force loading after Achilles tendon rupture repair with early functional mobilization
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-03)Background: Mechanical loading is essential for tendon healing and may explain variability in patient outcomes after Achilles tendon rupture (ATR) repair. However, there is no consensus regarding the optimal postoperative ... -
Knee extensor force production and discomfort during neuromuscular electrical stimulation of quadriceps with and without gluteal muscle co-stimulation
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-03)Purpose: To investigate whether Neuromuscular Electrical Stimulation (NMES) simultaneously applied on the quadriceps (Q) and gluteal (G) muscles, as compared to single Q-stimulation alters the knee extensor force production ... -
The effect of neuromuscular electrical stimulation on the human skeletal muscle transcriptome
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-03)Aim: The influence on acute skeletal muscle transcriptomics of neuromuscular electrical stimulation (NMES), as compared to established exercises, is poorly understood. We aimed to investigate the effects on global ... -
Impact of non-health sector determinants on child health the role of the Sustainable Development Goals : models, practices and perceptions in Cambodia and globally
(Inst för global folkhälsa / Dept of Global Public Health, 2024-05-02)Background. Child health has improved significantly over the last decades in Cambodia and globally. With the global adoption of the Sustainable Development Goals (SDGs) in 2015, a broad set of interlinked global goals to ... -
Surgical treatment of lung cancer
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-02)Background: Surgery is a central part in the treatment of lung cancer. There have been recent advances in minimal invasive and lung sparing surgical techniques, but evidence regarding safety and implementability is not ... -
Automated microfluidic-based production of PET radioligands for clinical and preclinical use
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-05-02)In recent decades, microfluidic technologies have been explored for PET radiopharmaceutical production. Moreover, radiotracer production models have been gradually transitioning from centralized to decentralized models ... -
Sexual health in young adult survivors of childhood cancer : prevalence, predictors and web-based support
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-02)Aim: The overall aim of this thesis was to investigate the prevalence of sexual activity and dysfunction in young adult survivors (19-40 years) of childhood cancer in comparison to the general population. A further aim was ... -
Exposures through drinking water and risk of chronic disease
(Institutet för miljömedicin / Institute of Environmental Medicine, 2024-05-02)Drinking water is the most important constituent of our diet. Yet, the importance of drinking water quality for population health is understudied. The overall aim of this thesis was to increase this knowledge by examining ... -
Exploring allergic and irritant contact dermatitis : biomarkers, mechanisms, and allergen uptake
(Institutet för miljömedicin / Institute of Environmental Medicine, 2024-04-30)Contact dermatitis (CD) is a common disease resulting from direct skin contact with allergens or irritants and greatly affects the life quality of suffering individuals. It is categorized into two main forms, namely allergic ... -
Immune responses after SARS-CoV-2 infection and/or vaccination
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-04-30)From the start of the COVID-19 pandemic, it was clear that studying immune responses after SARS-CoV-2 infection and later on, after vaccination, was of outmost importance in battling the pandemic. To understand immunological ... -
Neuromuscular electrical stimulation in physical inactivity
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-04-30)Physical inactivity and immobilization have emerged as major health issues. Neuromuscular electrical stimulation (NMES) is a potential treatment to prevent the negative effects of physical inactivity, such as muscle atrophy ... -
Catheter ablation of atrial fibrillation : methods for improving outcome
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2024-04-30)Introduction: The most common arrhythmia world-wide is atrial fibrillation (AF). The arrhythmia is diagnosed through an electrocardiogram (ECG). Patients with AF often experience symptoms including palpitations, dyspnoea, ... -
Volumetric and cortical brain development and outcome in children born extremely preterm
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-04-30)Children born extremely preterm (EPT) survive at an increasing rate. But they continue to have an increased risk for neurodevelopmental impairments. Magnetic resonance imaging (MRI) is used in a clinical setting, but can ... -
Psychological self-care in chronic conditions : development of digital interventions in type 1 diabetes and atopic dermatitis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-04-30)Background: Psychological interventions for somatic conditions have a long history with many successful examples, often based on cognitive behavioural therapy (CBT) However, psychologists are not commonly found in somatic ... -
Molecular and functional organization of the locomotor networks : from brainstem to spinal cord
(Inst för neurovetenskap / Dept of Neuroscience, 2024-04-30)Locomotion is a complex behavior that allows us to move and interact with the surroundings. In mammals, descending locomotor commands from the brainstem act directly onto spinal locomotor circuits to initiate or halt ... -
Neurocomputational modelling of human decision making and volition : from neural mechanisms to behavioral outcomes
(Inst för neurovetenskap / Dept of Neuroscience, 2024-04-30)In today's world, amidst the bombardment of information, the mental health and well-being of a society with higher level of responsibility hinge on a central issue related to decision making and human agency. The essence ... -
Advancing cardiovascular shear wave elastography and image registration : method development and safety evaluation
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-04-29)Cardiovascular disease remains the leading cause of death and disability worldwide, with its burden on health and healthcare systems projected to rise. In cardiovascular diagnostics and treatment strategy decisions, medical ... -
Innovations in pancreatology
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-04-26)In paper I, we explored the presence and potential significance of intracystic pancreatic microbiomes in patients with suspected pancreatic cystic neoplasms (PCNs), who underwent pancreatic surgery. Paired samples of ... -
Race against time : performance of emergency medical dispatch centres in out-of-hospital cardiac arrest
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2024-04-26)Background: Out-of-hospital cardiac arrest (OHCA) is an acute medical condition where the heart suddenly stops beating, thus causing blood circulation to cease in the body with irreversible brain damage and death if not ...