Now showing items 21-40 of 7343

  • Cohort profile : Swedish Twin Study on Prediction and Prevention of Asthma (STOPPA) 

    Almqvist, Catarina; Örtqvist, Anne K; Ullemar, Vilhelmina; Lundholm, Cecilia; Lichtenstein, Paul; Magnusson, Patrik K E (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
    Asthma is a common childhood disease and several risk factors have been identified, however the impact of genes and environment is not fully understood. The aim of the Swedish Twin study On Prediction and Prevention of ...
  • On the role of bioactive sphingolipids and their metabolizing enzymes in cancer 

    Ahmed, Dilruba (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2017-03-13)
    Ceramide is a family of closely related molecules, which are presumed to be in the center of sphingolipid metabolism. Among sphingolipid metabolites, several ceramide subspecies and sphingosine induce apoptosis, cell ...
  • Familial liability for eating disorders and suicide attempts : evidence from a population registry in Sweden 

    Yao, S.; Halkola, R.K.; Thornton, L.M.; Runfola, C.D.; D’Onofrio, B.M.; Almqvist, C.; Lichtenstein, P.; Sjölander, A.; Larsson, H.; Bulik, C.M. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-13)
    Importance: Suicide attempts are common in individuals with eating disorders. More precise understanding of the mechanisms underlying their co-occurrence is needed. Objective: To examine the association between ...
  • Association between parental age and asthma in a population-based register study 

    Almqvist, Catarina; Olsson, Henrik; Ullemar, Vilhelmina; D'Onfrio, Brian M; Frans, Emma; Lundholm, Cecilia (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-13)
    In a nationwide population-based study with family design, we found an association between decreasing parental age and asthma in early childhood. The effect was independent of familial and potentially confounding factors.
  • Persistence to antihypertensive drug treatment in Swedish primary care 

    Qvarnström, Miriam (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-03-10)
    Hypertension is The efficacy of antihypertensive drug therapy is undisputed, but large surveys report that one in four patients reach a target blood pressure of <140/90 mm Hg. Although there are several explanations to ...
  • Molecular determinants of endocannabinoid-mediated brain development 

    Calvigioni, Daniela (Inst för neurovetenskap / Dept of Neuroscience, 2017-03-10)
    The enchanting process of brain development entails a fragile and finite time window, throughout which biochemical imbalances and external insults can potentially affect developing neuronal circuits. Within the numerous ...
  • Lactobacillus mediated delivery of therapeutic peptides in the gastrointestinal tract 

    Lin, Yin (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2017-03-10)
    Lactobacilli are normal residents of the human gastrointestinal (GI) tract. Many species belonging to the genera Lactobacillus with health beneficial properties have been introduced as probiotics. Genetic engineering of ...
  • Encounters for learning and participation in breast cancer care 

    Engqvist Boman, Lena (Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2017-03-10)
    The overall aim of this thesis, is to increase the understanding of how women’s well-being, learning and participation during their breast cancer trajectory, especially in the context of short hospital stays, can be ...
  • On gender dysphoria 

    Dhejne, Cecilia (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2017-03-10)
    Gender identity refers to an innate and deeply felt psychological identification as a female, male, or some other non-binary gender. Gender identity may be congruent or incongruent with the sex assigned at birth. Gender ...
  • Identification of pathways of degeneration and protection in motor neuron diseases 

    Nichterwitz, Susanne (Inst för neurovetenskap / Dept of Neuroscience, 2017-03-09)
    Motor neuron diseases preferentially affect specific neuronal populations with distinct clinical features even if disease-causing genes are expressed in many cell types. In spinal muscular atrophy (SMA), somatic motor ...
  • Childhood attention-deficit/hyperactivity disorder symptoms and the development of adolescent alcohol problems : a prospective, population-based study of Swedish twins. 

    Quinn, Patrick; Pettersson, Erik; Lundström, Sebastian; Anckarsäter, Henrik; Långström, Niklas; Hellner Gumpert, Clara; Larsson, Henrik; Lichtenstein, Paul; D'Onofrio, Brian (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-09)
    Children with attention-deficit/hyperactivity disorder (ADHD) are at increased risk of problematic alcohol and other substance use in adolescence. This study used data from an ongoing, prospective, population-based twin ...
  • Cancer mortality and survival after cancer diagnosis by migration background and socioeconomic position in Sweden 

    Abdoli, Gholamreza (Institutet för miljömedicin / Institute of Environmental Medicine, 2017-03-09)
    Aims: The overall aim of this thesis was to investigate the risk of cancer mortality and survival after cancer diagnosis based on migration background and socioeconomic position in Sweden. We studied the effects of country ...
  • Childhood injury after a parental cancer diagnosis 

    Chen, R.; Regodon Wallin, A.; Sjolander, A.; Valdimarsdottir, U.; Ye, W.; Tiemeier, H.; Fall, K.; Almqvist, C.; Czene, K.; Fang, F. (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-09)
    A parental cancer diagnosis is psychologically straining for the whole family. We investigated whether a parental cancer diagnosis is associated with a higher-than-expected risk of injury among children by using a Swedish ...
  • Maltreatment-associated neurodevelopmental disorders : a co-twin control analysis. 

    Dinkler, Lisa; Lundström, Sebastian; Gajwani, Ruchika; Lichtenstein, Paul; Gillberg, Christopher; Minnis, Helen (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-09)
    BACKGROUND: Childhood maltreatment (CM) is strongly associated with psychiatric disorders in childhood and adulthood. Previous findings suggest that the association between CM and psychiatric disorders is ...
  • Heart failure : studies of prognosis and advanced therapy 

    Thorvaldsen, Tonje (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-03-09)
    Background Heart failure (HF) is a major health problem affecting 2-3% of the Western population. The clinical syndrome of HF is associated with reduced (HFrEF) or preserved (HFpEF) ejection fraction. Around 50% of ...
  • The role of estrogens and the microenvironment in lymphoma progression and drug sensitivity 

    Guan, Jiyu (Inst för biovetenskaper och näringslära / Dept of Biosciences and Nutrition, 2017-03-08)
    Lymphomas are a group of cancers which originate from lymphatic cells. More than 90% of the lymphomas belong to the group of Non-Hodgkin lymphoma (NHL), which in itself is a non-homogeneous group consisting of different ...
  • Genotype-phenotype characterization of familial hyperkinetic movement disorders : emphasis on ataxia and brain calcifications 

    Paucar, Martin (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2017-03-08)
    Differential diagnosis of familial chorea encompasses Huntington’s disease along with a group of conditions referred to as Huntington’s disease-like (HDL). One such HDL is an inherited prion disorder (IPD) caused by ...
  • The role of autophagy in cartilage physiology and metabolism : implications for growth and ageing 

    Vuppalapati, Karuna Kumari (Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2017-03-08)
    Cartilage is the main constituent of the embryonic skeleton. At the ends of long bones cartilage forms a growth plate consisting of chondrocytes in distinct stages of differentiation and arranged into three zones. These ...
  • A framework for organ dose estimation in x-ray angiography and interventional radiology based on dose-related data in DICOM structured reports. 

    Omar, Artur; Bujila, Robert; Fransson, Annette; Andreo, Pedro; Poludniowski, Gavin (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2017-03-07)
    Although interventional x-ray angiography (XA) procedures involve relatively high radiation doses that can lead to deterministic tissue reactions in addition to stochastic effects, convenient and accurate ...
  • Microscopic colitis 

    Mellander, Marie-Rose (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-03-06)
    Microscopic colitis (MC) is an inflammatory bowel disease (IBD) and a common cause of chronic non-bloody diarrhoea, especially in elderly women. There are two main subtypes, lymphocytic colitis (LC) and collagenous colitis ...