Now showing items 21-40 of 7291

  • CMV-infection in gay men with AIDS 

    Grützmeier, Sven (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-02-03)
    Background: Before the era of combination therapy (c-ART) more than 90 % of the patients with HIV-infection died of one or more opportunistic infections (OI). We and others noted early on that CMV was an important pathogen ...
  • Medical screening in dental settings 

    Friman, Göran (Inst för odontologi / Dept of Dental Medicine, 2017-02-03)
    Background Findings have shown medical screening in dental settings to be cost-effective by achieving both financial savings and health benefits. The general purpose of this thesis was to study the possibility of early ...
  • Bipolar disorder and lithium treatment : etiologies and consequences 

    Song, Jie (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-02-02)
    Bipolar disorder is a chronic disabling psychiatric disorder marked by episodic disruptive mood swings, accompanied by disturbances in cognition and behavior. Without effective treatment, bipolar disorder can have devastating ...
  • Falls in wheelchair users with spinal cord injury : incidence, risks and concerns 

    Butler Forslund, Emelie (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-02)
    Background: Knowledge about falls and related injuries in persons with spinal cord injuries (SCI) is limited, especially concerning wheelchair users. Further research is required in order to develop future prevention ...
  • Suicide : a pharmacoepidemiological database study in the region Friuli Venezia Giulia, Italy 

    Castelpietra, Giulio (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2017-02-02)
    Aims: The objective of this thesis is to examine the relationship between suicide and health care in Italy’s Friuli Venezia Giulia (FVG) region. First, it explores the correlation between suicide rates and antidepressant ...
  • Transcriptional regulation of neuronal differentiation in the developing CNS 

    Rraklli, Vilma (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2017-02-02)
    The central nervous system (CNS) is responsible for our intellectual and cognitive functions and it comprises the brain and spinal cord. Generation of the CNS occurs during embryonic development from the neural tube that ...
  • Memory B-cell function and antibody profiles in malaria : their role in protection against disease in infancy 

    Lugaajju, Allan (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-02-02)
    Malaria infection is of huge public health importance in developing countries, including Uganda. Antibody immunity assumes a paramount part in the disease control however there’s a great need to study components of ...
  • Meaning-making in integrative health care : studies on patients’ and practitioners’ experiences 

    Andermo, Susanne (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-02-01)
    Background and aim: Patients living with chronic pain often turn both to conventional and complementary health care. Integrative health care combines conventional and complementary therapies in the clinical care of ...
  • Disability pension due to common mental disorders : subsequent psychiatric morbidity and suicidal behaviour 

    Rahman, Syed (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2017-01-30)
    Background: Mental diagnoses have become the most common disability pension (DP) diagnoses in OECD countries. Up to half of DP due to mental diagnoses are due to common mental disorders (CMDs). So far, research has mainly ...
  • Hatha yogic exercises for physical function in healthy individuals and patients with obstructive respiratory disorders 

    Papp, Marian E (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2017-01-27)
    Background and aim: The use of hatha yogic exercises (YE) is increasing, with both healthy individuals and patients asking for alternative treatments and other means of prevention and exercise. To investigate the physical ...
  • Systemic lupus erythematosus : biomarkers and biologics 

    Parodis, Ioannis (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-01-26)
    Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, predominantly affecting women of childbearing age. The pathogenesis of SLE is multifactorial, and the clinical phenotype and course vary considerably ...
  • SOX transcription factors : multifaceted regulators of central nervous system development 

    Zaouter, Cécile (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2017-01-26)
    The central nervous system (CNS) is composed of three major cell types, namely neurons, astrocytes and oligodendrocytes that are mainly generated during embryonic stages by multipotent neural progenitor cells (NPCs). The ...
  • The role of interferon-regulated genes in the immune system 

    Sjöstrand, Maria (Inst för medicin, Solna / Dept of Medicine, Solna, 2017-01-25)
    Type I interferons (IFNs) are potent inducers of the first-line defense against pathogens. Their activity leads to the up- and downregulation of a large number of genes with various effects on the immune system, including ...
  • Traumatic patellar dislocation in children : epidemiology, risk factors, the MPFL and treatment outcome 

    Askenberger, Marie (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-01-25)
    The knee joint is one of the most common injury sites in children, with the spectrum of injuries differing from those in adults. Traumatic lateral patellar dislocation (LPD) is the most common serious injury; the incidence ...
  • Psychiatric comorbidity in multiple sclerosis : biological and epidemiological aspects 

    Brenner, Philip (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2017-01-23)
    Multiple sclerosis (MS) is a chronic, neuroinflammatory disease and one of the leading reasons for neurological disability among young people in the Western World. MS patients commonly experience neuropsychiatric symptoms ...
  • Targeting DNA repair pathways for cancer therapy 

    Eshtad, Saeed (Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2017-01-20)
    Accumulation of genomic mutations is the consequence of failure in DNA repair as well as increased exposure to endogenous/environmental mutagens. DNA repair pathways safeguard the human genome from such mutagens, and thereby ...
  • The role of KIF1Bß in neuroblastoma tumour suppression during sympathetic neuron development 

    Fell, Stuart (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2017-01-19)
    Neuroblastoma, the most common extra-cranial childhood tumour, is believed to arise from precursor cells of the sympathetic nervous system (neuroblasts). Hemizygous loss of chromosome 1p36 strongly correlates with poor ...
  • Troponin elevation in acute stroke : clinical characteristics and the link to cancer-associated neutrophil extracellular traps 

    Thålin, Charlotte (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2017-01-18)
    Elevated plasma levels of troponin, a marker of myocardial injury, are a frequent observation in stroke patients. Despite several reports on an adverse short-term prognosis, however, the significance of troponin elevation ...
  • Depression or anxiety in adult twins is associated with asthma diagnosis but not with offspring asthma 

    Tedner, SG; Lundholm, Cecilia; Olsson, Henrik; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-17)
    BACKGROUND: Asthma is common in both children and adults in the Western world, just like anxiety and depression. While some research has revealed that these diseases might share important environmental and ...
  • Evaluation of a metal-on-metal total hip arthroplasty 

    Dahlstrand, Henrik (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2017-01-17)
    Background After the introduction of the Metasul system by Weber in 1988, total hip arthroplasty (THA) with metal-on-metal (MoM) bearings became increasingly popular in the 1990s. MoM bearings aimed to reduce the ...