Artiklar / Articles - C6 (IMM): Recent submissions

Now showing items 21-40 of 41

    • Registers of the Swedish total population and their use in medical research 

      Ludvigsson, Jonas F; Almqvist, Catarina; Edstedt Bonamy, Anna-Karin; Ljung, Rickard; Michaëlsson, Karl; Neovius, Martin; Stephansson, Olof; Ye, Weimin (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-28)
      The primary aim of the Swedish national population registration system is to obtain data that (1) reflect the composition, relationship and identities of the Swedish population and (2) can be used as the basis for correct ...

    • Similar familial risk in multiple sclerosis subgroups 

      Song, Jie; Karrenbauer, Virginija; Manouchehrinia, Ali; Almqvist, Catarina; Hillert, Jan; Westerlind, Helga (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)
      Background: A subgroup of patients diagnosed with multiple sclerosis (MS) present with no oligoclonal bands (OCB) in the cerebrospinal fluid (CSF). Several studies report different clinical characteristics and genetic ...

    • Air pollution exposure during pregnancy and childhood autistic traits in four European population-based cohort studies : the ESCAPE project 

      Guxens, Monica; Ghassabian, Akhgar; Gong, Tong; Garcia-Esteban, Raquel; Porta, Daniela; Giorgis-Allemand, Lise; Almqvist, Catarina; Aranbarri, Aritz; Beelen, Rob; Badaloni, Chiara; Cesaroni, Giulia; de Nazelle, Audrey; Estarlich, Marisa; Forastiere, Francesco; Forns, Joan; Gehring, Ulrike; Ibarluzea, Jesus; Jaddoe, Vincent W; Korek, Michal; Lichtenstein, Paul; Nieuwenhuijsen, Mark J; Rebagliato, Marisa; Slama, Remy; Tiemeier, Henning; Verhulst, Frank C; Volk, Heather E; Pershagen, Göran; Brunekreef, Bert; Sunyer, Jordi (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
      Background: Prenatal exposure to air pollutants has been suggested as a possible etiologic factor for the occurrence of autism spectrum disorder. Objectives: We aimed to assess whether prenatal air pollution exposure ...

    • Perinatal exposure to traffic-related air pollution and autism spectrum disorders 

      Gong, Tong; Dalman, Christina; Wicks, Susanne; Dal, Henrik; Magnusson, Cecilia; Lundholm, Cecilia; Almqvist, Catarina; Pershagen, Göran (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-14)
      Background: Studies from the United States indicate that exposure to air pollution in early life is associated with autism spectrum disorders (ASD) in children, but the evidence is not consistent with European data. ...

    • The influence of childhood asthma on puberty and height in Swedish adolescents 

      Protudjer, Jennifer; Lundholm, Cecilia; Bergström, Anna; Kull, Inger; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-16)
      BACKGROUND: Evidence relating to the effect of asthma on puberty or height is inconclusive. We aimed to examine whether the exposure of childhood asthma, including timing and phenotypes, and inhaled corticosteroid (ICS) ...

    • Asthma during pregnancy in a population-based study : pregnancy complications and adverse perinatal outcomes 

      Rejnö, Gustaf; Lundholm, Cecilia; Gong, Tong; Larsson, Kjell; Saltvedt, Sissel; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      BACKGROUND: Asthma is one of the most common chronic diseases, and prevalence, severity and medication may have an effect on pregnancy. We examined maternal asthma, asthma severity and control in relation to ...

    • Antibiotic treatment and length of hospital stay in relation to delivery mode and prematurity 

      Ahlén, Katia M; Örtqvist, Anne K; Gong, Tong; Wallas, Alva K; Ye, Weimin; Lundholm, Cecilia; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)
      AIM: To investigate how 1) maternal delivery mode and 2) prematurity in infants are associated to antibiotic treatment and length of hospital stay. METHODS: Women having given birth and infants 0-12 months discharged ...

    • Exome sequencing of contralateral breast cancer identifies metastatic disease 

      Klevebring, Daniel; Lindberg, Johan; Rockberg, Julia; Hilliges, Camilla; Hall, Per; Sandberg, Maria; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-05)
      Women with contralateral breast cancer (CBC) have significantly worse prognosis compared to women with unilateral cancer. A possible explanation of the poor prognosis of patients with CBC is that in a subset of patients, ...

    • Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility 

      Adel Fahmideh, Maral; Lavebratt, Catharina; Schüz, Joachim; Röösli, Martin; Tynes, Tore; Grotzer, Michael A; Johansen, Christoffer; Kuehni, Claudia E; Lannering, Birgitta; Prochazka, Michaela; Schmidt, Lisbeth S; Feychting, Maria (Institutet för miljömedicin / Institute of Environmental Medicine, 2016-10-05)
      Knowledge on the role of genetic polymorphisms in the etiology of pediatric brain tumors (PBTs) is limited. Therefore, we investigated the association between single nucleotide polymorphisms (SNPs), identified by candidate ...

    • Heritability and confirmation of genetic association studies for childhood asthma in twins. 

      Ullemar, Vilhelmina; Magnusson, Patrik K E; Lundholm, Cecilia; Zettergren, Anna; Melén, Erik; Lichtenstein, Paul; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-03-17)
      BACKGROUND: Although the genetics of asthma has been extensively studied using both quantitative and molecular genetic analysis methods, both approaches lack studies specific to the childhood phenotype and including other ...

    • Breastfeeding, asthma, and allergy : a tale of two cities 

      Brew, Bronwyn K; Kull, Inger; Garden, Frances L; Almqvist, Catarina; Bergström, Anna; Lind, Tomas; Webb, Karen L; Wickman, Magnus; Marks, Guy B (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2015-07-21)
      BACKGROUND: The effect of breastfeeding duration on subsequent asthma and allergy remains the subject of much controversy. OBJECTIVE: To investigate whether differences in study design or disease-related exposure ...

    • Marital status and survival after oesophageal cancer surgery : a population-based nationwide cohort study in Sweden 

      Brusselaers, Nele; Mattsson, Fredrik; Johar, Asif; Wikman, Anna; Lagergren, Pernilla; Lagergren, Jesper; Ljung, Rickard (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2015-03-11)
      Objectives A beneficial effect of being married on survival has been shown for several cancer types, but is unclear for oesophageal cancer. The objective of this study was to clarify the potential influence of the marital ...

    • Variability in the CIITA gene interacts with HLA in multiple sclerosis 

      Gyllenberg, Alexandra; Piehl, Fredrik; Alfredsson, Lars; Hillert, Jan; Bomfim, Izaura Lima; Padyukov, Leonid; Orho-Melander, Marju; Lindholm, Eero; Landin-Olsson, Mona; Lernmark, Åke; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group; Olsson, Tomas; Kockum, Ingrid (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2015-02-09)
      The human leukocyte antigen (HLA) is the main genetic determinant of multiple sclerosis (MS) risk. Within the HLA, the class II HLA-DRB1*15:01 allele exerts a disease-promoting effect, whereas the class I HLA-A*02 allele ...

    • Puberty and asthma in a cohort of Swedish children 

      Protudjer, Jennifer; Lundholm, Cecilia; Bergström, Anna; Kull, Inger; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-03-14)

    • Cat and house dust mite allergen content is stable in frozen dust over time 

      Merritt, Anne-Sophie; Andersson, Niklas; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-01-16)
      Background: Dust from indoor environments consists of animal allergens, pollen, endotoxins and other substances which may exacerbate symptoms in sensitive individuals. In prospective cohort studies, dust is often collected ...

    • The Swedish Twin Registry : establishment of a biobank and other recent developments 

      Magnusson, Patrik K E; Almqvist, Catarina; Rahman, Iffat; Ganna, Andrea; Viktorin, Alexander; Walum, Hasse; Halldner, Linda; Lundström, Sebastian; Ullén, Fredrik; Långström, Niklas; Larsson, Henrik; Nyman, Anastasia; Hellner Gumpert, Clara; Råstam, Maria; Anckarsäter, Henrik; Cnattingius, Sven; Johannesson, Magnus; Ingelsson, Erik; Klareskog, Lars; de Faire, Ulf; Pedersen, Nancy L; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-12-20)
      The Swedish Twin Registry (STR) today contains more than 194,000 twins and more than 75,000 pairs have zygosity determined by an intra-pair similarity algorithm, DNA, or by being of opposite sex. Of these, approximately ...

    • Development and comorbidity of eczema, asthma and rhinitis to age 12 : data from the BAMSE birth cohort 

      Ballardini, Natalia; Kull, Inger; Lind, Tomas; Hallner, Eva; Almqvist, Catarina; Östblom, Eva; Melén, Erik; Pershagen, Göran; Lilja, Gunnar; Bergström, Anna; Wickman, Magnus (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-12-04)
      BACKGROUND: Allergy-related diseases are a public health issue, but knowledge on development and comorbidity among children is scarce. The aim was to study the development of eczema, asthma and rhinitis in relation to sex ...

    • LifeGene : a large prospective population-based study of global relevance 

      Almqvist, Catarina; Adami, Hans-Olov; Franks, Paul W; Groop, Leif; Ingelsson, Erik; Kere, Juha; Lissner, Lauren; Litton, Jan-Eric; Maeurer, Markus; Michaëlsson, Karl; Palmgren, Juni; Pershagen, Göran; Ploner, Alexander; Sullivan, Patrick F; Tybring, Gunnel; Pedersen, Nancy L (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2013-09-25)
      Studying gene-environment interactions requires that the amount and quality of the lifestyle data is comparable to what is available for the corresponding genomic data. Sweden has several crucial prerequisites for comprehensive ...

    • Doxorubicin sensitizes human tumor cells to NK and T cell-mediated killing by augmented TRAIL-receptor signaling 

      Wennerberg, Erik; Sarhan, Dhifaf; Carlsten, Mattias; Kaminskyy, Vitaliy; D'Arcy, Pádraig; Zhivotovsky, Boris; Childs, Richard; Lundqvist, Andreas (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2013-07-25)
      Doxorubicin (DOX) is an anthracycline antibiotic that is widely used to treat different types of malignancy. In this study, it was studied whether DOX could be used to render tumor cells susceptible to apoptosis by NK and ...

    • Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile 

      Lundberg, Karin; Bengtsson, Camilla; Kharlamova, Nastya; Reed, Evan; Jiang, Xia; Källberg, Henrik; Pollak-Dorocic, Iskra; Israelsson, Lena; Kessel, Christoph; Padyukov, Leonid; Holmdahl, Rikard; Alfredsson, Lars; Klareskog, Lars (Inst för medicin, Solna / Dept of Medicine, Solna, 2013-07-04)
      OBJECTIVES: To increase understanding of the aetiology and pathogenesis of rheumatoid arthritis (RA), genetic and environmental risk factors for RA subsets, defined by the presence or absence of different anticitrullinated ...