Doktorsavhandlingar / Doctoral Theses - SwePub: Recent submissions
Now showing items 61-80 of 9353
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Sexual health in young adult survivors of childhood cancer : prevalence, predictors and web-based support
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-02)Aim: The overall aim of this thesis was to investigate the prevalence of sexual activity and dysfunction in young adult survivors (19-40 years) of childhood cancer in comparison to the general population. A further aim was ... -
Exposures through drinking water and risk of chronic disease
(Institutet för miljömedicin / Institute of Environmental Medicine, 2024-05-02)Drinking water is the most important constituent of our diet. Yet, the importance of drinking water quality for population health is understudied. The overall aim of this thesis was to increase this knowledge by examining ... -
Exploring allergic and irritant contact dermatitis : biomarkers, mechanisms, and allergen uptake
(Institutet för miljömedicin / Institute of Environmental Medicine, 2024-04-30)Contact dermatitis (CD) is a common disease resulting from direct skin contact with allergens or irritants and greatly affects the life quality of suffering individuals. It is categorized into two main forms, namely allergic ... -
Immune responses after SARS-CoV-2 infection and/or vaccination
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-04-30)From the start of the COVID-19 pandemic, it was clear that studying immune responses after SARS-CoV-2 infection and later on, after vaccination, was of outmost importance in battling the pandemic. To understand immunological ... -
Neuromuscular electrical stimulation in physical inactivity
(Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-04-30)Physical inactivity and immobilization have emerged as major health issues. Neuromuscular electrical stimulation (NMES) is a potential treatment to prevent the negative effects of physical inactivity, such as muscle atrophy ... -
Catheter ablation of atrial fibrillation : methods for improving outcome
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2024-04-30)Introduction: The most common arrhythmia world-wide is atrial fibrillation (AF). The arrhythmia is diagnosed through an electrocardiogram (ECG). Patients with AF often experience symptoms including palpitations, dyspnoea, ... -
Volumetric and cortical brain development and outcome in children born extremely preterm
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-04-30)Children born extremely preterm (EPT) survive at an increasing rate. But they continue to have an increased risk for neurodevelopmental impairments. Magnetic resonance imaging (MRI) is used in a clinical setting, but can ... -
Psychological self-care in chronic conditions : development of digital interventions in type 1 diabetes and atopic dermatitis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-04-30)Background: Psychological interventions for somatic conditions have a long history with many successful examples, often based on cognitive behavioural therapy (CBT) However, psychologists are not commonly found in somatic ... -
Molecular and functional organization of the locomotor networks : from brainstem to spinal cord
(Inst för neurovetenskap / Dept of Neuroscience, 2024-04-30)Locomotion is a complex behavior that allows us to move and interact with the surroundings. In mammals, descending locomotor commands from the brainstem act directly onto spinal locomotor circuits to initiate or halt ... -
Neurocomputational modelling of human decision making and volition : from neural mechanisms to behavioral outcomes
(Inst för neurovetenskap / Dept of Neuroscience, 2024-04-30)In today's world, amidst the bombardment of information, the mental health and well-being of a society with higher level of responsibility hinge on a central issue related to decision making and human agency. The essence ... -
Advancing cardiovascular shear wave elastography and image registration : method development and safety evaluation
(Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-04-29)Cardiovascular disease remains the leading cause of death and disability worldwide, with its burden on health and healthcare systems projected to rise. In cardiovascular diagnostics and treatment strategy decisions, medical ... -
Innovations in pancreatology
(Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-04-26)In paper I, we explored the presence and potential significance of intracystic pancreatic microbiomes in patients with suspected pancreatic cystic neoplasms (PCNs), who underwent pancreatic surgery. Paired samples of ... -
Race against time : performance of emergency medical dispatch centres in out-of-hospital cardiac arrest
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2024-04-26)Background: Out-of-hospital cardiac arrest (OHCA) is an acute medical condition where the heart suddenly stops beating, thus causing blood circulation to cease in the body with irreversible brain damage and death if not ... -
Exploring cannabinoids for indolent B-cell lymphomas
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2024-04-26)The overexpression of cannabinoid receptors is well described in several indolent lymphomas but the relevance of this finding is more uncertain. Our group has previously shown that mantle cell lymphoma (MCL)-derived cell ... -
Advancements in detection of performance enhancing drugs in dried blood spots : focusing on erythropoietin
(Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2024-04-26)The use of erythropoietin (EPO) for performance enhancing purposes is detected mainly in urine and serum samples in anti-doping laboratories. However, dried blood spots (DBS) have emerged as a potential additional sample ... -
DNA tools for imaging and manipulation of biological samples
(Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2024-04-26)Spatial organization within biological systems is important for understanding mechanisms underlying health and disease. This thesis investigates the role of spatial distribution at cellular and molecular levels, utilizing ... -
Multiple sclerosis, viruses, and B cell depleting therapy : a meeting at the immune system
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-04-25)Multiple sclerosis (MS) is a highly heterogeneous disease with a complex and undiscovered etiology. Two of the strongest established risk factors for developing MS are carriage of the HLA-DRB1*15:01 allele and Epstein-Barr ... -
The motives and ethical justifiability of treating patients with borderline personality disorder under compulsory care
(Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2024-04-25)This thesis aims to investigate what motives psychiatrists have for detaining patients with BPD under compulsory care. Also, to examine hospital staff’s experiences of treating patients with BPD under involuntary care and ... -
High-capacity in vitro models for the assessment of pain-related mechanisms
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2024-04-25)Chronic pain affects one in five people. Yet, new efficient drugs with fewer adverse effects remain an unmet need for chronic pain. In vitro models that closer recapitulate relevant disease mechanisms are suggested as a ... -
Health consequences of gender-based harassment at work
(Institutet för miljömedicin / Institute of Environmental Medicine, 2024-04-25)Background: Experiences at work with gender-based violence and harassment (GBVH) from superiors, co-workers or third parties are common. This includes a range of verbal or physical behaviors that can be of a sexual nature ...