Now showing items 1-20 of 8280

    • Serious and violent offending : psychological risk factors and treatment effectiveness 

      Lardén, Martin (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-05-15)
      Background: Violent crime causes extensive suffering and costs to individuals and societies and is a major global health issue. Prevention of violence should occur at several levels, and effective psychological interventions ...
    • Novel intervention approaches after recent exposure to trauma 

      Bragesjö, Maria (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-05-12)
      Background: The life-time incidence of exposure to traumatic events is high and can have a profound negative impact on mental health. The majority of individuals exposed to trauma will go through a process of natural ...
    • Human papillomavirus as a target for cancer prevention 

      Hortlund, Maria (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2021-05-12)
      If we would know more about virus causing cancer, we would have the possibility to prevent the disease. Human Papillomavirus (HPV) causes cervical cancer and is one of the world’s most common sexually transmitted diseases ...
    • Closing the abdominal wall in high-risk abdominal surgery 

      Söderbäck, Harald (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-05-12)
      Background: Incisional hernia and Wound dehiscence are potentially serious complications to midline incisions. Recent studies have shown that a meticulous suturing technique can reduce the rate of these complications ...
    • Gateway to the gut : alterations in saliva in inflammatory bowel disease 

      Majster, Mirjam (Inst för odontologi / Dept of Dental Medicine, 2021-05-12)
      Inflammatory bowel disease (IBD), which consists of Crohn’s disease and ulcerative colitis, is a chronic immune-mediated disease thought to result from genetic and environmental interaction which influence the commensal ...
    • Mastication in jaw muscle pain 

      Al Sayegh, Samaa (Inst för odontologi / Dept of Dental Medicine, 2021-05-12)
      Background: Integrated Pain Adaptation Models suggest a possible pain-motor interaction. Mechanisms affecting the jaw muscle spindles seem to affect the ability to bite and chew, suggesting that jaw muscle pain may be a ...
    • Emotion dysregulation, self-image, and eating disorders 

      Monell, Elin (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-05-12)
      Background: Eating disorders (EDs) are complex psychiatric disorders that entail great suffering, high prevalence of comorbid psychiatric and somatic conditions, and increased mortality. The understanding of how EDs ...
    • The preterm infant : evaluating and developing non-invasive respiratory strategies to avoid mechanical ventilation 

      Donaldsson, Snorri (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-11)
      Avoiding mechanical ventilation of preterm infants is important to prevent morbidity and mortality. Non-invasive ventilation and CPAP has been shown to be superior to intubation and mechanical ventilation in preventing ...
    • Psoriasis : observational studies on clinical course, economic burden and treatment 

      Svedbom, Axel (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-11)
      Better understanding of long-term prognosis, clinical course, comorbidities, economic burden, and treatment of psoriasis, can improve care of patients with the disease and may inform decisions on resource allocation, ...
    • Socioeconomic status and myocardial infarction : influence on secondary prevention and prognosis 

      Ohm, Joel (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-11)
      Background and Aims In the wealth of research undertaken on myocardial infarctions (MIs), secondary prevention is less well studied. Incidence and death from MI have declined substantially in the past decades due to the ...
    • Upholding family relationships in a context of increasing awareness of parental illness 

      Oja, Charlotte (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2021-05-11)
      Background Children are affected when parents are ill and health care professionals are bound by law to consider children’s need for information on their parent’s illness. Effective interventions are available in settings ...
    • Hereditary, molecular and prognostic factors in endometrial cancer 

      Castro Wersäll, Ofra (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-10)
      Aims: The overall aim of this thesis is to describe and evaluate hereditary uterine cancer syndrome both independent of and in relation to hereditary patterns of Lynch and/or Cowden syndrome for the purpose of recognizing ...
    • Environmental arsenic exposure in humans : toxicity and adaptation in the Bolivian Andes 

      De Loma Olson, Jessica (Institutet för miljömedicin / Institute of Environmental Medicine, 2021-05-07)
      Arsenic, a potent toxicant and carcinogen, is naturally present in soil and leaches into groundwater. More than 140 million people worldwide are exposed to arsenic through drinking water. How well humans metabolize arsenic ...
    • RNA-mediated gene regulation in Neisseria meningitidis and other nasopharyngeal pathogens 

      Eichner, Hannes (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2021-05-07)
      Neisseria meningitidis is a transient commensal bacterium of the upper respiratory tract and spreads through respiratory secretions produced by the carrier. While mostly harmless, the bacterium can cause invasive meningococcal ...
    • Novel injectable calcium sulfate depot formulations for local cancer treatment 

      Grudén, Stefan (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2021-05-07)
      In the present thesis, a novel drug delivery technology named NanoZolid® based on hydrating inorganic calcium sulfate, is investigated. NanoZolid is injected as a liquid suspension of calcium sulfate, which solidifies ...
    • Assessment of prognostic factors of prostate cancer : limitations and possibilities of morphology 

      Swanberg, Daniela (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2021-05-07)
      Prostate cancer is a leading cause of cancer morbidity and mortality. It is a morphologically, genetically, and clinically heterogeneous disease. Stage and grade are important predictors of patient outcome. Extraprostatic ...
    • Characterization and long-term follow-up of Pediatric Acute-onset Psychiatric Syndrome (PANS) 

      De Visscher, Caroline (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2021-05-07)
      Background Pediatric acute-onset neuropsychiatric syndrome (PANS) is a cluster of psychiatric and somatic symptoms of proposed autoimmune etiology. It remains a descriptive entity, still of unclear validity and uncertain ...
    • Translational studies on mechanical hemostasis and coagulopathy in trauma 

      Brännström, Andreas (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-05-07)
      Trauma, in terms of physical injury, is the leading cause of death and disability among children and young adults worldwide. Hemorrhage and coagulation dysfunction are two important causes of preventable deaths after ...
    • Adenomyosis-Imaging features for diagnosing the disease and treatment effects of bromocriptine 

      Andersson, Johanna (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2021-05-07)
      Background: Adenomyosis is a benign uterine disease, causing various symptoms including heavy menstrual bleeding (HMB) and pelvic pain. In affected women, endometrial glands and stroma are located in the myometrium surrounded ...
    • Impact of genetic and environmental factors in intestinal inflammation 

      Diaz Perez, Oscar Eduardo (Inst för medicin, Solna / Dept of Medicine, Solna, 2021-05-07)
      The gastrointestinal tract, is continuously exposed to a wide variety of stimuli, including dietary-derived metabolites, environmental compounds and the microbiota. Since these antigens can be beneficial or detrimental ...