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  • eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences. 

    Pelechano, Vicent; Alepuz, Paula (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-10-31)
    eIF5A is an essential protein involved in protein synthesis, cell proliferation and animal development. High eIF5A expression is observed in many tumor types and has been linked to cancer metastasis. Recent studies have ...
  • From transcriptional complexity to cellular phenotypes : lessons from yeast 

    Pelechano, Vicent (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-10-27)
    Pervasive transcription has been reported in many eukaryotic organisms, revealing a highly interleaved transcriptome organization that involves thousands of coding and non-coding RNAs. However, to date, the biological ...
  • Helicobacter pylori eradication in the Swedish population 

    Doorakkers, Eva; Lagergren, Jesper; Gajulapuri, Vijaya Krishna; Callens, Steven; Engstrand, Lars; Brusselaers, Nele (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell BiologyInst för molekylär medicin och kirurgi / Dept of Molecular Medicine and SurgeryKing's College LondonGhent University Belgium, 2017-04-28)
    Objectives: Helicobacter pylori (H. pylori) is associated with peptic ulcers and gastric cancer and its eradication aims to prevent these conditions. The recommended eradication regimen is triple therapy, consisting of ...
  • Eradication of Helicobacter pylori and gastric and oesophageal cancer : a systematic review and meta-analysis of cohort studies 

    Doorakkers, Eva; Lagergren, Jesper; Engstrand, Lars; Brusselaers, Nele (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell BiologyInst för molekylär medicin och kirurgi / Dept of Molecular Medicine and SurgeryKing's College London, 2017-04-28)
    Background: Helicobacter pylori (H. pylori) is associated with an increased risk of gastric adenocarcinoma and gastric mucosa associated lymphoid tissue (MALT) lymphoma, and a seemingly decreased risk of oesophageal ...
  • RhoD regulates cytoskeletal dynamics via the actin nucleation–promoting factor WASp homologue associated with actin Golgi membranes and microtubules 

    Gad, Annica K.B.; Nehru, Vishal; Ruusala, Aino; Aspenström, Pontus (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2013-03-25)
    The Rho GTPases have mainly been studied in association with their roles in the regulation of actin filament organization. These studies have shown that the Rho GTPases are essential for basic cellular processes, such ...

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