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  • High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation 

    Agostinho, Ana; Manneberg, Otto; van Schendel, Robin; Hernández-Hernández, Abrahan; Kouznetsova, Anna; Blom, Hans; Brismar, Hjalmar; Höög, Christer (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular BiologyScience for Life Laboratory, 2016-12-07)
    During meiosis, cohesin complexes mediate sister chromatid cohesion (SCC), synaptonemal complex (SC) assembly and synapsis. Here, using super-resolution microscopy, we imaged sister chromatid axes in mouse ...
  • TFAM forces mtDNA to make a U-turn 

    Hällberg, B. Martin; Nils-Göran, Larsson (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular BiologyInst för laboratoriemedicin / Dept of Laboratory MedicineMax Planck Institute for Biology of Ageing, Köln, Germany., 2014-08-04)
    The mammalian mitochondrial transcription factor A (TFAM) is encoded in the nucleus and imported into mitochondria, where it functions as an activator of mtDNA transcription and packages mtDNA into DNA-protein aggregates ...
  • Making proteins in the powerhouse 

    Hällberg, Martin; Larsson, Nils-Göran (Inst för laboratoriemedicin / Dept of Laboratory MedicineInst för cell- och molekylärbiologi / Dept of Cell and Molecular BiologyMax Planck Institute for Biology of Ageing, Cologne, Germany, 2014-08-04)
    Understanding regulation of mitochondrial DNA (mtDNA) expression is of considerable interest as mitochondrial dysfunction is important in human pathology and ageing. Similar to the situation in bacteria, there is no ...

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