Now showing items 1-20 of 154

    • Pregnancy outcomes in women with a prior cervical intraepithelial neoplasia grade 3 diagnosis : a nationwide population-based cohort study with sibling comparison design 

      He, Wei; Sparén, Pär; Fang, Fang; Sengpiel, Verena; Strander, Björn; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-11-27)
      Background: Treatment of cervical intraepithelial neoplasia grade 3 (CIN3) removes or destroys part of the cervix and might subsequently influence pregnancy outcomes. Objective: To investigate pregnancy outcomes in women ...
    • Heritability of mammographic breast density, density change, microcalcifications, and masses 

      Holowko, Natalie; Eriksson, Mikael; Kuja-Halkola, Ralf; Azam, Shadi; He, Wei; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-11-27)
      Background: Mammographic features influence breast cancer risk and are used in risk prediction models. Understanding how genetics influence mammographic features is important since the mechanisms through which they are ...
    • Chemotherapy, genetic susceptibility, and risk of venous thromboembolism in breast cancer patients 

      Brand, Judith S; Hedayati, Elham; Humphreys, Keith; Ludvigsson, Jonas F; Johansson, Anna L V; Bergh, Jonas; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-10-25)
      Purpose: Venous thromboembolism (VTE) is highly heritable and a serious complication of cancer and its treatment. We examined the individual and joint effects of chemotherapy and genetic susceptibility on VTE risk in ...
    • Maternal asthma and early fetal growth : the MAESTRO study 

      Rejnö, Gustaf; Lundholm, Cecilia; Saltvedt, Sissel; Larsson, Kjell; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-02-08)
      Background: Several maternal conditions can affect fetal growth, and asthma during pregnancy is known to be associated with lower birth weight and shorter gestational age. Objective: In a new Swedish cohort study ...
    • Paediatric asthma and non-allergic comorbidities : a review of current risk and proposed mechanisms 

      Brew, Bronwyn K; Osvald, Emma Caffrey; Gong, Tong; Hedman, Anna M; Holmberg, Kirsten; Larsson, Henrik; Ludvigsson, Jonas F; Mubanga, Mwenya; Smew, Awad I; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-24)
      It is increasingly recognized that children with asthma are at a higher risk of other non-allergic concurrent diseases than the non-asthma population. A plethora of recent research has reported on these comorbidities and ...
    • Season of birth, childhood asthma and allergy in a nationwide cohort : mediation through lower respiratory infections 

      Almqvist, Catarina; Ekberg, Sara; Rhedin, Samuel; Fang, Fang; Fall, Tove; Lundholm, Cecilia (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-23)
      Background: Previous studies have suggested an association between season of birth and risk of childhood asthma and allergic disease. The association may be modified by birth year and region, or mediated by respiratory ...
    • Understanding the relationship between asthma and autism spectrum disorder : a population-based family and twin study 

      Gong, Tong; Lundholm, Cecilia; Lundström, Sebastian; Kuja-Halkola, Ralf; Taylor, Mark; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-17)
      Background: There is some evidence that autism spectrum disorder (ASD) frequently co-occurs with immune-mediated conditions including asthma. We aimed to explore the familial co-aggregation of ASD and asthma using different ...
    • Limited association between markers of stress during pregnancy and fetal growth in 'Born into Life' : a new prospective birth cohort 

      Smew, Awad I; Hedman, Anna M; Chiesa, Flaminia; Ullemar, Vilhelmina; Andolf, Ellika; Pershagen, Göran; Almqvist, Catarina (Institutet för miljömedicin / Institute of Environmental MedicineInst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and BiostatisticsInst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2023-01-17)
      Aims: We aimed to investigate the associations between perceived maternal stress or salivary cortisol levels during pregnancy and birthweight. Methods: In 2010-2012, we recruited 92 women living in Stockholm, Sweden, ...
    • Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age 

      Merid, Simon Kebede; Novoloaca, Alexei; Sharp, Gemma C; Küpers, Leanne K; Kho, Alvin T; Roy, Ritu; Gao, Lu; Annesi-Maesano, Isabella; Jain, Pooja; Plusquin, Michelle; Kogevinas, Manolis; Allard, Catherine; Vehmeijer, Florianne O; Kazmi, Nabila; Salas, Lucas A; Rezwan, Faisal I; Zhang, Hongmei; Sebert, Sylvain; Czamara, Darina; Rifas-Shiman, Sheryl L; Melton, Phillip E; Lawlor, Debbie A; Pershagen, Göran; Breton, Carrie V; Huen, Karen; Baiz, Nour; Gagliardi, Luigi; Nawrot, Tim S; Corpeleijn, Eva; Perron, Patrice; Duijts, Liesbeth; Nohr, Ellen Aagaard; Bustamante, Mariona; Ewart, Susan L; Karmaus, Wilfried; Zhao, Shanshan; Page, Christian M; Herceg, Zdenko; Jarvelin, Marjo-Riitta; Lahti, Jari; Baccarelli, Andrea A; Anderson, Denise; Kachroo, Priyadarshini; Relton, Caroline L; Bergström, Anna; Eskenazi, Brenda; Soomro, Munawar Hussain; Vineis, Paolo; Snieder, Harold; Bouchard, Luigi; Jaddoe, Vincent W; Sørensen, Thorkild I A; Vrijheid, Martine; Arshad, S Hasan; Holloway, John W; Håberg, Siri E; Magnus, Per; Dwyer, Terence; Binder, Elisabeth B; DeMeo, Dawn L; Vonk, Judith M; Newnham, John; Tantisira, Kelan G; Kull, Inger; Wiemels, Joseph L; Heude, Barbara; Sunyer, Jordi; Nystad, Wenche; Munthe-Kaas, Monica C; Räikkönen, Katri; Oken, Emily; Huang, Rae-Chi; Weiss, Scott T; Antó, Josep Maria; Bousquet, Jean; Kumar, Ashish; Söderhäll, Cilla; Almqvist, Catarina; Cardenas, Andres; Gruzieva, Olena; Xu, Cheng-Jian; Reese, Sarah E; Kere, Juha; Brodin, Petter; Solomon, Olivia; Wielscher, Matthias; Holland, Nina; Ghantous, Akram; Hivert, Marie-France; Felix, Janine F; Koppelman, Gerard H; London, Stephanie J; Melén, Erik (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-03-05)
      Background: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated ...
    • Circulating proteins as predictors of cardiovascular mortality in endstage renal disease 

      Feldreich, Tobias; Nowak, Christoph; Fall, Tove; Carlsson, Axel C; Carrero, Juan-Jesus; Ripsweden, Jonaz; Qureshi, Abdul Rashid; Heimbürger, Olof; Barany, Peter; Stenvinkel, Peter; Vuilleumier, Nicolas; Kalra, Philip A; Green, Darren; Ärnlöf, Johan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-02-24)
      Introduction: Proteomic profiling of end-stage renal disease (ESRD) patients could lead to improved risk prediction and novel insights into cardiovascular disease mechanisms. Plasma levels of 92 cardiovascular disease-associated ...
    • Lipids, apolipoproteins, and prognosis of amyotrophic lateral sclerosis 

      Ingre, Caroline; Chen, Lin; Zhan, Yiqiang; Termorshuizen, Jet; Yin, Li; Fang, Fang (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-06-08)
      Objective: To determine whether lipids and apolipoproteins predict prognosis of patients with amyo- trophic lateral sclerosis in a cohort study of 99 patients with amyotrophic lateral sclerosis who were diagnosed during ...
    • Risk factors and tumor characteristics of interval cancers by mammographic density 

      Holm, Johanna; Humphreys, Keith; Li, Jingmei; Ploner, Alexander; Cheddad, Abbas; Eriksson, Mikael; Törnberg, Sven; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-23)
      Purpose: To compare tumor characteristics and risk factors of interval breast cancers and screen-detected breast cancers, taking mammographic density into account. Patients and Methods: Women diagnosed with invasive ...
    • Associations of breast cancer risk prediction tools with tumor characteristics and metastasis 

      Holm, Johanna; Li, Jingmei; Darabi, Hatef; Eklund, Martin; Eriksson, Mikael; Humphreys, Keith; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-23)
      Purpose: The association between established risk factors for breast cancer and subtypes or prognosis of the disease is not well known. We analyzed whether the Tyrer-Cuzick–predicted 10-year breast cancer risk score (TCRS), ...
    • Breast cancer genetic risk profile is differentially associated with interval and screen-detected breast cancers 

      Li, Jingmei; Holm, Johanna; Bergh, Jonas; Eriksson, Mikael; Darabi, Hatef; Lindström, Linda Sofie; Törnberg, Sven; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-17)
      Background: Polygenic risk profiles computed from multiple common susceptibility alleles for breast cancer have been shown to identify women at different levels of breast cancer risk. We evaluated whether this genetic risk ...
    • Assessment of breast cancer risk factors reveals subtype heterogeneity 

      Holm, Johanna; Eriksson, Louise; Ploner, Alexander; Eriksson, Mikael; Rantalainen, Mattias; Li, Jingmei; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-17)
      Subtype heterogeneity for breast cancer risk factors has been suspected, potentially reflecting etiological differences and implicating risk prediction. Reports are conflicting regarding presence of heterogeneity for many ...
    • Time-dependent risk of depression, anxiety, and stress-related disorders in patients with invasive and in situ breast cancer 

      Yang, Haomin; Brand, Judith S; Fang, Fang; Chiesa, Flaminia; Johansson, Anna L V; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-17)
      Despite concerns about the mental health of breast cancer patients, little is known regarding the temporal risk pattern and risk factors of common mental disorders among these patients. We estimated standardized incidence ...
    • Time from breast cancer diagnosis to therapeutic surgery and breast cancer prognosis : a population-based cohort study 

      Eriksson, Louise; Bergh, Jonas; Humphreys, Keith; Wärnberg, Fredrik; Törnberg, Sven; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2020-04-17)
      Theoretically, time from breast cancer diagnosis to therapeutic surgery should affect survival. However, it is unclear whether this holds true in a modern healthcare setting in which breast cancer surgery is carried out ...
    • Effects of inhaled corticosteroids on DNA methylation in peripheral blood cells in children with asthma 

      Kere, Maura; Gruzieva, Olena; Ullemar, Vilhelmina; Söderhäll, Cilla; Greco, Dario; Kull, Inger; Bergström, Anna; Pershagen, Göran; Almqvist, Catarina; Melén, Erik (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2019-09-25)
    • Sibship and dispensing patterns of asthma medication in young children : a population based study 

      Dahlén, Elin; Lundholm, Cecilia; Wikström Jonsson, Eva; Kull, Inger; Wettermark, Björn; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-08-06)
      Purpose: Our aim was to study the association between sibship and dispensing patterns of asthma medication in young children, focusing on incidence and persistence, and taking sibship status, asthma diagnoses, and siblings’ ...
    • Cesarean delivery, preterm birth and risk of food allergy : nationwide Swedish cohort study of over 1 million children 

      Mitselou, Niki; Hallberg, Jenny; Stephansson, Olof; Almqvist, Catarina; Melén, Erik; Ludvigsson, Jonas F (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-08-06)
      Background & Objectives: Little is known about early life risk factors for food allergy in children. We examined the association between perinatal characteristics and future risk of food allergy in offspring. Methods: ...