Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience: Recent submissions
Now showing items 1-20 of 578
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Reduced working hours and stress in the Swedish social services
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-04-01)Background: Since a financial crisis in the 1990’s employees in the Swedish public sector have suffered from work stress and related consequences such as long-term sick leave. Reduced working hours has long been debated ... -
Molecular approaches for characterization, diagnosis and therapy of allergy to pets
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-03-06)Allergy to furred animals is a common affliction, where up to 20% of the population in affluent countries are sensitized to one or more pet allergens. Several causative allergens from an array of species have been identified, ... -
Penumbra oxygen metabolism and acute neuroinflammation in ischemic stroke : MRI and PET imaging of a M2 occlusion model in rat
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-03-04)Acute ischemic stroke (AIS) is caused by the sudden occlusion of a major artery of the brain, and results in infarction and severe ischemia within affected brain regions. If ischemic regions are rapidly revascularized, ... -
Sudden unexpected death in epilepsy, incidence, circumstances and risk factors
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-02-12)Although Sudden Unexpected Death in Epilepsy (SUDEP) has attracted increasing attention from the scientific community during the last 20 years, important gaps in knowledge still exist that hamper the development of methods ... -
Excessive worry in adolescents and adults : development and evaluation of theory-driven treatments
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-02-12)Background: Worry is common among both adolescents and adults, and excessive worry is related to a number of mental health problems. Current pharmacological and psychological treatments for worry are moderately effective, ... -
Sickness absence, disability pension, and permanent medical impairment among car occupants injured in a crash
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-02-06)Background: Health loss in the road transport system is a major global public health problem, with approximately 1.35 million people killed annually, and it is also the fifth leading cause of overall burden of disease. ... -
A behavioral defense against disease
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-01-31)Animals, including humans, have evolved under the continuous selection pressure posed by pathogens. As a result, we have developed a set of physiological mechanisms to combat pathogens – the immune system. However, engaging ... -
Cognitive behavioral therapy for stress-related disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-01-16)Background: Stress-related disorders in the form of adjustment disorder (AD) and exhaustion disorder (ED) are prevalent and associated with significant suffering, functional impairment and high societal costs. Cognitive ... -
Demyelinating conditions regulated by ROS pathways outside and inside the brain
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-01-14)Multiple sclerosis (MS) is a chronic inflammatory condition of the central nervous system with immune-mediated damage on myelinated nerve tracts. Accumulating evidence support a role for autoreactive T-lymphocytes ... -
Family-based prevention of childhood obesity : long-term outcomes, challenges and implications for future research
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2020-01-03)Background: Childhood obesity is considered to be one of the most serious health challenges of the 21st century. There have been indications that the prevalence has reached a plateau in high-income countries, yet the ... -
Too tired to talk? : sleep, fatigue, and social functioning
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-21)Sleep has been shown to have many health promoting functions, and is vital for the maintenance of physiological, cognitive, and emotional well-being. Much of what we know about sleep derives from studies showing what happens ... -
Getting close with discomfort : exposure therapy for fibromyalgia
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-13)Background: Fibromyalgia (FM) is a common and debilitating disorder for which there are currently no treatments available that are satisfyingly effective. Cognitive behavior therapy (CBT) might be a promising treatment ... -
Immune cells and stem cells in spinal cord injury : defining spinal cord injury associated microglia
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-13)Traumatic spinal cord injury (SCI) commonly results from falls, sport activities or traffic accidents and most often results in lost sensory, motor and/or autonomic functions below the level of injury. The cellular- and ... -
Methodological issues in psychological treatment research : applications to gambling research and therapist effects
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-12)Over the last couple of decades evidence-based psychotherapies have flourished, and there are now therapies that are well-established for a wide range of problems. At the same time the mental-health burden is still enormous, ... -
Interactions between the opioid and serotonin systems in chronic pain : quantitative live cell study by Fluorescence Cross-Correlation Spectroscopy (FCCS)
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-11)Chronic pain is a major health issue worldwide. It enacts considerable suffering on the affected individuals and significantly increases the societal burden, as it is the most common reason why individuals seek sick leave ... -
Cognitive deficits in alcohol use disorder : etiology and treatment
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-11-04)Alcohol use disorder (AUD) is a psychiatric disorder characterized by a loss of control over drinking, tolerance, withdrawal and negative psychological, physical and social consequences due to excessive alcohol consumption. ... -
Risk factors and health consequences of obsessive-compulsive and chronic tic disorders
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-10-25)Background: Obsessive-compulsive disorder (OCD) is a severe and heterogenous mental disorder characterized by intrusive thoughts, urges or images, followed by repetitive behaviors aimed to reduce the associated anxiety. ... -
Involving concerned significant others in the treatment of problem gambling
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-10-18)Background: Problem gambling (PG) is a worldwide phenomenon that affects both gamblers and their concerned significant others (CSOs). Apart from financial difficulties, problem gambling is associated with disrupted ... -
Internet-delivered cognitive behaviour therapy for paediatric anxiety disorders in clinical settings : increasing access to evidence-based treatments
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-10-17)Background: Paediatric anxiety disorders are common, impairing and associated with a societal and economic burden. Even though there are efficacious treatments to treat these disorders, access to them are limited. ... -
Modelling and quantifying brain connectivity and dynamics with applications in aging and ADHD
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2019-10-04)Human brain is a complex organ and made up of integrative networks encompassing a large number of regions. These regions communicate with each other to share information involved in complex cognitive processes. Functional ...