Doktorsavhandlingar / Doctoral Theses - K6 (KBH): Recent submissions
Now showing items 41-60 of 487
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Magnetic resonance imaging and advanced imaging assessment of the growth plate in the adolescent and young adult
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-11-03)The growth plate is a cartilaginous structure located between the metaphysis and epiphysis in long bones. It is the centre for longitudinal growth. Longitudinal growth has a biphasic pattern with a peak during foetal and ... -
Rare pediatric movement disorders : clinical aspects of genotype, phenotype, and assessment
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-10-26)Pediatric movement disorders are defined by an impaired ability to initiate and control movements. Dystonia, one of these disorders, may cause a life-long severe motor disability. Pharmacological treatment is often ... -
Targeting ALK and WIP1 : neuroblastoma precision medicine under development
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-10-26)Neuroblastoma is the childhood solid tumor accountable for the largest number of deaths, calling for improved treatment. Some genetic alterations are considered crucial in driving initiation and progression of neuroblastoma. ... -
Posterior reversible encephalopathy syndrome and other severe central nervous system adverse events in the NOPHO ALL2008 protocol : clinical and radiological findings, genetic risk factors and prognosis
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-10-18)Background: The advances in the therapeutic protocols for pediatric acute lymphoblastic leukemia (ALL) have led to a current survival rate of more than 90% in developed countries. Treatment periods are, however, long and ... -
Specific IgE-profiles and allergy prediction
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-09-22)Presence of antibodies of type Immunoglobulin E (IgE-ab), often called sensitization, is common and often precede development of atopic disease, including food allergy. While not all IgE-sensitized individuals develop food ... -
Omega-3 fatty acids in the treatment of childhood cancer
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-08-31)Childhood cancer is the primary cause of deaths among Swedish children. Advances in treatment regimens have improved cure rate considerably in the latest decades. Consequently, childhood cancer survivors are a growing ... -
Effects of lifestyle intervention in overweight women with polycystic ovary syndrome : aspects on reproduction, metabolism, psychological well-being and sleep
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-30)Lifestyle intervention is the first line treatment for many symptoms in women with polycystic ovary syndrome (PCOS). However, the efficacy of this treatment in comparison to minimal intervention for improving aspects such ... -
Environmental etiologies of autism and other neurodevelopmental conditions : twin studies of the cumulative effect of early medical events
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-24)Background: Neurodevelopmental conditions (NDC), such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), are characterized by alterations in the architecture, functioning, and maturation ... -
Experimental studies of growth response to hormonal treatment
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-20)Statural growth occurs as a result of the collective growth of long bones and the axial skeleton. Linear bone growth occurs at both ends of the bones in a thin cartilaginous structure termed the growth plate, located between ... -
Educational inclusion for students with neurodevelopmental conditions
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-20)Introduction: Inclusive education is the response to the human rights movement that requested equal rights to general education for all students, independent of their prerequisites and/or disabilities. Inclusion is different ... -
A study of incidence, causative factors, symptoms, and prognosis in epilepsy with onset in the first two years of life
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-19)Background: The motivation to start this thesis work came from the meetings with infants just having presented with epileptic seizures and from speaking to their parents. I found two issues to be particularly urgent. The ... -
Contraceptive counseling and use with a focus on migrant women in Sweden
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-17)INTRODUCTION: Sweden has a high unmet need of contraception resulting in high rates of induced abortions compared with other Northern European countries. The highest abortion rates are seen among women 25-29 years of age. ... -
Immediate skin-to-skin contact for very preterm and low birth weight infants : from newborn physiology to mortality reduction
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-05-17)There is a contrast between the incidence of low birth weight and the contents and outcomes of neonatal care in high- versus middle- and low-income countries. Most of the neonatal deaths worldwide are attributed to low ... -
Prognostic factors in endometrial cancer
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-22)Endometrial cancer (EC) is the most common malignancy of the female reproductive system in Sweden. Patients with EC generally have a good prognosis, though some face recurrence and have a lower survival rate despite ... -
Nasal CPAP support of newborn infants : measurements of interface leakage and performance of selected systems
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-20)Objective: The most common treatment for newborns in respiratory distress is nasal continuous positive airway pressure (nCPAP). Comparing clinical studies have shown a better outcome and a lower risk of chronic lung disease ... -
Congenital adrenal hyperplasia : pre-and postnatal treatment effects on cognition, behavior and brain resting-state functional connectivity
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-14)Congenital adrenal hyperplasia (CAH), an autosomal recessive disorder affecting adrenal steroid synthesis, is linked to impaired adrenal synthesis of cortisol and aldosterone. The increased production of androgen precursors ... -
Molecular and clinical studies of intestinal malrotation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-13)Intestinal malrotation (IM) can present as a potentially life-threatening condition with midgut volvulus and need of immediate surgery, but also as a chronic condition with long-lasting symptoms. It is a well-known neonatal ... -
Modern contraceptive use among female refugee adolescents in northern Uganda : prevalence, effect of peer counselling, adherence, and experiences
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-11)Background: Adolescent pregnancies have remained high globally, with the highest rates occurring in low- and middle-income countries and humanitarian settings. The high adolescent pregnancy rates have been attributed to ... -
HPV and potential prognostic markers in primary vaginal carcinoma
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-08)The overall aim of this PhD thesis is to evaluate HPV status and immunohistochemical expression of different biomarkers, including tumor suppressor p16, proliferation marker Ki67, molecular markers in the LRIG family, ... -
Neurofeedback and working memory training in children and adolescents with ADHD
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-03-04)Background: ADHD is one of the most prevalent neurodevelopmental disorders among children and adolescents. Although pharmacological interventions are highly effective in attenuating symptoms of inattention and impulsivity, ...