Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health: Recent submissions
Now showing items 161-180 of 536
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Molecular and functional studies on human embryo implantation : targets for infertility and fertility regulation
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-10-27)Background: An estimated one in four couples globally suffers from infertility or fertility related issues and rate of global infertility is about 10-15%. Despite the best optimization of assisted reproductive technique ... -
Genetic studies of susceptibility to inflammation, autoimmunity, and hematological malignancy
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-10-27)The immune system represents the body’s defense against infectious organisms. Inborn defects of the immune system, called primary immunodeficiencies (PIDs), are a heterogeneous group of Mendelian disorders. Clinically, ... -
Neonatal complications following birth by vacuum extraction
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-10-25)Background: Vacuum extraction is a common method of delivery presently accounting for approximately 7 percent of all deliveries in Sweden. It is considered an important and safe obstetric procedure, although both maternal ... -
Diabetes during childhood and adolescence : studies of insulin treatment, patient-reported outcomes, and evaluation of an empowerment-based education
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-10-24)There is a lack of studies demonstrating positive effects on glycaemic control and HRQoL in children and adolescents starting CSII treatment. Guidelines recommend measuring perceived HRQoL routinely. It is important to ... -
Quality and efficacy of early intensive autism intervention : a matter of trust, knowledge, and supervision?
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-10-05)In contrast to previous research, mainly focusing on child characteristics and on quantity of treatment as essential moderating and predicting outcome factors of Early Intensive Behavioral Intervention (EIBI), the overall ... -
Evaluation of function in individuals with knee osteoarthritis
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-09-27)Introduction: Osteoarthritis, the most common joint disease, results in joint pain and limited function. In clinical practice, the array of measurements used to evaluate function are generally restricted to patient-reported ... -
Diverse effects of endocrine-disruptive chemicals on Leydig and adrenocortical cell steroidogenesis in rodents and humans
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-09-22)We are living in a man-made world and often exposed to different chemicals known as endocrine disrupting chemicals (EDCs) that negatively influence our hormonal system. These compounds have the potential to interrupt a ... -
Are carriers of CYP21A2 mutations less vulnerable to psychological stress? A population-based national cohort study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-06-14)Background: Congenital adrenal hyperplasia (CAH) is one of the most common monogenic autosomal recessive disorders with an incidence of one in 15 000. About one in 70 individuals in the general population are carriers of ... -
Emotion recognition and expression in autism spectrum disorder : significance, complexity, and effect of training
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-05-23)The overall scientific aim of this thesis is to examine emotion recognition in children with Autism Spectrum Disorder (ASD), its specificity to ASD and connection to other cognitive functions, as well as to map the effects ... -
Register-based studies of hypospadias
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-05-19)Hypospadias is a common genital malformation ofcomplex origin. It is characterized by misplacement of the urethral orifice, proximal to the tip of the glans penis, and is most often accompanied by a cleaved prepuce and ... -
New approaches on fetal and maternal intrapartum monitoring
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-05-18)Background: Intrapartum fetal monitoring aims to prevent adverse outcomes due to intrapartum asphyxia. Cardiotocography (CTG) is an established method for intrapartum monitoring. The method has high sensitivity, but low ... -
A three dimensional scaffold for single staged tissue engineering
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-05-05)Study I. Aims: Evaluate a collagen-PCL scaffold with minced bladder mucosa in vitro. M&M: Minced tissue was cultured on top of the scaffold. Scaffold properties were evaluated. Results: Good proliferation. Multilayered ... -
Progesterone receptor modulators in contraception : clinical implications of ovarian and endometrial effects
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-05-02)Background: Emergency contraception (EC) offers a last chance to prevent an unwanted pregnancy after unprotected sexual intercourse (UPSI) but before pregnancy occurs, for example after contraceptive failure, non-use of ... -
Long-term effects of mother-infant psychoanalysis
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-04-28)This thesis is a long-term follow-up study of mothers and infants with “baby worries” or mother-infant relational disturbances, who took part in a Randomized Controlled Trial when the children were, on average, five months ... -
Prenatal nicotine exposure and effects on the health of the newborn
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2017-03-30)Maternal smoking is one of the most important preventable risk factors in pregnancy. Whether it is nicotine or combustion products, or possibly both, that cause the adverse effects is not clear. The common substance in ... -
Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency : a Swedish population-based national cohort study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-29)CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. OBJECTIVE: ... -
Registers of the Swedish total population and their use in medical research
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-28)The primary aim of the Swedish national population registration system is to obtain data that (1) reflect the composition, relationship and identities of the Swedish population and (2) can be used as the basis for correct ... -
Hypospadias as a novel feature in spinal bulbar muscle atrophy
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)Spinal and bulbar muscle atrophy (SBMA) is an X-linked neuromuscular disorder caused by CAG repeat expansions in the androgen receptor (AR) gene. The SBMA phenotype consists of slowly progressive neuromuscular symptoms and ... -
Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)Context: Reports on mortality in patients with congenital adrenal hyperplasia (CAH) are lacking. Objective: To study mortality and causes of death in CAH. Design, Setting and Participants: We studied patients ... -
Exposure to air pollution from traffic and neurodevelopmental disorders in Swedish twins
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-17)Background: Recent studies have reported associations between air pollution exposure and neurodevelopmental disorders in children but the role of pre- and postnatal exposure has not been elucidated. Aim: We aimed ...