Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health: Recent submissions
Now showing items 1-20 of 536
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Multiomic analysis of T cells in response to cancers and microbes
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-08-05)The human immune system consists of various cell subsets, cytokines and their interactions. Traditionally researchers focus on one compartment at a time, however, with the advance in high-throughput, multi-omics techniques, ... -
Long-term cardiovascular assessment in women with preeclampsia
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-22)Background: Preeclampsia (PE) is one of the most common medical multi-organ, pregnancy-specific disorder. PE is associated with endothelial dysfunction, elevated blood pressure, and inflammation. In addition to vascular ... -
Testosterone is performance enhancing in women but challenging to detect in doping analyses
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-22)BACKGROUND: There is an ongoing debate whether women with testosterone (T) within the male range shall be allowed to compete in the female class in sports. In men, T has an ergogenic effect, but the effect of T in young ... -
Bone health impairment in childhood cancer : from preclinical studies to clinical insights
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-20)Survival outcomes in childhood cancer have significantly improved over recent decades. While this is a remarkable achievement, it has also led to a growing number of survivors who face a great risk of long-term morbidities. ... -
Sexual health in young adult survivors of childhood cancer : prevalence, predictors and web-based support
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-02)Aim: The overall aim of this thesis was to investigate the prevalence of sexual activity and dysfunction in young adult survivors (19-40 years) of childhood cancer in comparison to the general population. A further aim was ... -
Volumetric and cortical brain development and outcome in children born extremely preterm
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-04-30)Children born extremely preterm (EPT) survive at an increasing rate. But they continue to have an increased risk for neurodevelopmental impairments. Magnetic resonance imaging (MRI) is used in a clinical setting, but can ... -
Impact of childhood leukemia and its treatment on Nordic children and families : the consent process, toxicity, and quality of life
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-04-24)Background: The survival rate in acute lymphoblastic leukemia (ALL) has improved remarkably over the last half-century and is now reaching above 90%. The treatment is lengthy, however, and with a high risk of short- and ... -
Immediate skin-to-skin contact after a very preterm birth : supporting the parent-infant relationship
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-04-16)Background: Preterm birth poses challenges that may negatively affect parental mental health and infant development. A well-functioning parent-infant relationship can mitigate the risk of preterm birth on infant development, ... -
From preschool wheeze to childhood asthma : the role of genetics and environmental factors
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-03-26)Background: Respiratory illness with wheeze is very common at preschool age and is often the first clinical manifestation of asthma. Two-thirds of preschool wheezers outgrow their symptoms by their sixth birthday whereas ... -
Family planning service – addressing potential barriers
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-03-18)Background: Access to family planning service is crucial for reproductive health. Family planning service include contraceptive methods as well as safe methods for pregnancy termination when needed. It was estimated in ... -
Genetic and epigenetic risk factors for asthma in infancy and childhood
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-03-18)Asthma is among the most common non-communicable diseases, with an increasing prevalence worldwide. The pathophysiology behind the disease is heterogeneous, including risk factors like genes, sex, allergies, virus infections, ... -
Visual perception in infancy and its links to later autism
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-01-24)Alterations in primary sensory areas of the brain have been suggested to be at the roots of the well-documented visual perceptual differences in autism. However, despite the possible key role these sensory processing ... -
Interventional closure of persistent foetal cardiac shunts including PDA and PFO : study of outcome, complications and novel methods
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-12-28)Background: Persistent foramen ovale (PFO) and persistent ductus arteriosus (PDA) are two of the most common congenital heart defects (CHD). The incidence of PFO is reported to be between 10% and 35% (1, 2). In term infants, ... -
Vulvar cancer : patterns of recurrence, quality of life and extended indications for the sentinel node technique
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-12-18)Background: Vulvar cancer is a rare malignancy and few studies have addressed the course of disease and the impact of physical and psychological symptoms on healthrelated quality of life (HRQOL) over time. In addition, ... -
Building a family with gamete donation : perspectives of parents and offspring
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-11-17)The aim of this thesis was to investigate the long-term psychosocial consequences for heterosexual couple families following oocyte donation (OD) and sperm donation (SD), in the context of the Swedish legislation. An ... -
Factors associated with preschool wheeze developing into school-age asthma
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-11-13)Preschool wheeze affects one third of all toddlers up to the age of three years and half of the children before six years of age. Approximately one third of these children will develop asthma in school age, and several ... -
Newborn respiratory support using distending pressure : the effect of interfaces and system design on performance and outcome
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-11-09)Preterm infants often require respiratory support after birth due to lung immaturity. The preferred method of providing respiratory support to breathing infants in respiratory distress is non-invasively with continuous ... -
Moral dilemmas and ethics support in childhood cancer care : a relational perspective
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-11-09)Background: Despite the high survival rate, childhood cancers are still life-threatening diseases that affect everyone involved. The child’s treatment period is intensive and highly specialised, involving various procedures. ... -
Impact of body mass index on outcome, toxicity and pharmacokinetics in patients with acute lymphoblastic leukemia
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-10-27)Background: Overweight and obesity are growing health problems. Obesity has been associated with both a higher risk of contracting cancer and increased cancer-related mortality in adults. The impact in children with cancer, ... -
Immune variation in infectious disease and during development early in life
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-10-25)The human immune system is not only a complex system but a highly dynamic and heterogenous one. It consists of many specialized cells that stimulate and inhibit each other via proteins and physical interactions. And ...