Licentiatavhandlingar / Licentiate Theses - K2 (MedS)
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Recent submissions
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Utveckling av instrument och bedömning av sjuksköterskestudenters kunskaper och färdigheter att genomföra venös provtagning och insättning av perifer venkateter
(Inst för medicin, Solna / Dept of Medicine, Solna, 2015-08-18)Det finns ett uppenbart behov av att hitta objektiva bedömningsunderlag för sjuksköterskestudenters kunskaper efter genomgångna kliniska kurser. Genom att utveckla och validera instrument som kan användas i utbildningen ... -
Efficacy of artemisinin based combination therapy and effectiveness of rapid diagnostic test for management of patients with plasmodium falciparum malaria in Zanzibar
(Institutionen för medicin / Department of Medicine, 2009-05-19)Background: Due to rapid spread of antimalarial drug resistance to Plasmodium falciparum malaria many African countries have recently changed their first-line treatment policy to artemisinin-based combination therapy (ACT). ... -
Myasthenia gravis : clinical aspects and possible involvement of prolactin
(Institutionen för medicin / Department of Medicine, 2006-09-15)Myasthenia gravis (MG) is an autoimmune disease characterized by the production of antibodies against the skeletal muscle acetylcholine receptor (AChR). MG is usually associated with thymic disorders including thymoma ... -
Methods and detection of endogenous peptides in the CNS and GI tract
(Institutionen för medicin / Department of Medicine, 2006-11-15)Endogenous peptides, such as enkephalins, endorphins and orexins modulate a variety of biological processes; these peptides are found in the central nervous system and periphery, including the gastrointestinal tract. One ... -
Effects of high glucose on platelet activation
(Institutionen för medicin / Department of Medicine, 2006-08-07)Diabetes mellitus (DM) is associated with increased cardiovascular mortality and morbidity, due to diabetic angiopathy. Hyperglycaemia is one of the factors that may cause platelet dysfunction in diabetic patients. This ... -
Characterisation of psoriasis lesions by protein expression profiling
(Institutionen för medicin / Department of Medicine, 2006-05-26)Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic ... -
A study of lymphocyte functions in multiple myelopma
(Institutionen för medicin / Department of Medicine, 2006-02-07)Multiple myeloma (MM) is a lymphoproliferative disorder which is characterized by an accumulation of clonotypic plasma, cells in the bone marrow leading to an overproduction of monoclonal immunoglobulin (mIg). The disease ... -
Individualized leukapheresis of hematopoietic cells for cellular therapies
(Institutionen för medicin / Department of Medicine, 2005-11-24)Hematopoietic stem and progenitor cells from blood (HSC) are collected by leukapheresis from patients after mobilization with G-CSF +/- chemotherapy to be used in autologous transplantation. The established method to measure ... -
Structural and biophysical studies of pneumococcal capsular surface proteins
(Inst för medicin, Solna / Dept of Medicine, Solna, 2014-10-15)Streptococcus pneumoniae (pneumococcus) is a major human pathogen and a leading cause of morbidity and mortality worldwide, especially in children and the elderly. The casualties due to respiratory infections are estimated ... -
Living with chronic kidney disease : perceptions of illness and health-related quality of life
(Inst för medicin, Solna / Dept of Medicine, Solna, 2012-11-12)This thesis comprises two studies concerning illness perceptions and perceived health-related quality of life (HRQoL) in patients with chronic kidney disease (CKD). The overall aim was to evaluate psychometric properties ... -
Spread and distribution of drug resistance and compensatory mutations in Plasmodium falciparum
(Inst för medicin, Solna / Dept of Medicine, Solna, 2012-05-08)In 2010 there were an estimated 216 million cases of malaria worldwide. In Honduras there were ~9000 cases of which 88% were due to Plasmodium vivax mono-infection. Chloroquine (CQ) resistant Plasmodium falciparum have ... -
Studies on 15-lipoxygenase in dendritic cells and leukotriene receptors in Hodgkin lymphoma
(Institutionen för medicin / Department of Medicine, 2006-12-19)Classical Hodgkin lymphoma (cHL) is histologically characterized by a minority of malignant cells, the so-called Hodgkin-Reed Sternberg (H-RS) cells, surrounded by inflammatory cells such as T lymphocytes, eosinophils, ... -
Autoantibodies in congenital heart block
(Institutionen för medicin / Department of Medicine, 2009-11-20)Neonatal lupus erythematosus (NLE) affects neonates of Ro/SSA and La/SSB positive women. NLE is associated with several clinical manifestations including skin rash, cytopenia and congenital heart block (CHB). CHB is the ... -
Studies on the activation of cytosolic phospholipase A2 and 15-lipoxygenase-1
(Institutionen för medicin / Department of Medicine, 2006-11-28)Arachidonic acid is a polyunsaturated fatty acid, which has four double bonds and belongs to the omega-6 family of fatty acids. Even if it can be formed in humans from one essential fatty acid, the linoleic acid, most of ...