Doktorsavhandlingar / Doctoral Theses - H7 (MedH): Recent submissions
Now showing items 321-330 of 330
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Novel immunological mechanisms and factors in systemic lupus erythematosus-related cardiovascular disease
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2006-03-31)Systemic Lupus Erythematosus (SLE) is a clinical syndrome of autoimmune origin. It manifests in diverse clinical and serological patterns and is considered to represent a prototype multisystemic autoimmune disease. The ... -
Strategies for management of EBV and adenovirus infections after allogeneic stem cell transplantation
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2010-05-25)Viral infections are one of the challenges that can threaten successful allogeneic HSCT especially during the period of immune reconstitution resulting in a high mortality risk. Adenoviruses and EBV are important viruses ... -
Pulmonary tuberculosis and Pneumocystis jiroveci pneumonia in HIV-infected patients in Ethiopia
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2007-02-12)The objective of this study initially was to determine the prevalence of culture-verified pulmonary tuberculosis in TB suspects and investigate the impact of human immunodeficiency virus (HIV) infection on the prevalence, ... -
Alcohol and inflammation : a study of effects of ethanol on endothelial and epithelial cell functions
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2007-10-26)Although short–term alcohol drinking causes euphoric and stress relieving effects, alcohol abuse is a major risk factor for neurobehavioural, liver and muscle injury as well as reduced host defence with enhanced susceptibility ... -
Leukemia inhibitor factor (LIF) and gp130 in early defence against HIV-1 infection
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2006-11-23)Leukemia inhibitor factor (LIF) is a polyfunctional cytokine that belongs to the IL-6 family which mainly signals through the Jak/Stat pathway via the gp130/LIFR-α heterodimer. The focus of my research has been to ... -
Chronic intestinal pseudo-obstruction and enteric dysmotility : aspects on patients' health-care use, coping capacity and quality of life
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2009-08-14)Aims of the thesis: To measure health care consumption before and after the introduction of a specialized day-care unit and to investigate if patients with chronic intestinal pseudo-obstruction (CIP) differ from those with ... -
Analgetic and algetic effects of adenosine in healthy volunteers and patients with coronary disease
(Institutionen för medicin, Huddinge Sjukhus / Department of Medicine at Huddinge University Hospital, 2007-11-23)Background: Adenosine is a bimodal neuromodulator with algesic and analgesic effects. The different effects of adenosine are partly due to the route of administration. Low-dose adenosine infusion induces analgesia at the ... -
Nephrin-mutations in congenital nephrotic syndrome of the Finnish type and cell lineage specific gene regulation
(Institutionen för medicinsk biokemi och biofysik (MBB) / Department of Medical Biochemistry and Biophysics, 2005-04-21)Kidneys, the main excretory organs in vertebrates, play central role in removing water soluble metabolic waste products from the organism. Many acquired and inherited renal diseases in man lead to kidney dysfunction and ... -
Studies on arachidonic acid metabolism in normal and malignant hematopoietic cells
(Inst för medicinsk biokemi och biofysik / Dept of Medical Biochemistry and Biophysics, 2010-01-15)This thesis deals with the metabolism of arachidonic acid via the 5-lipoxygenase- and the 15-lipoxygenase-1 pathways in normal and malignant hematopoietic cells. The first part of the thesis (papers I & II) describes ... -
Non-urgent and heavy use of the emergency department : intervention and follow-up studies
(Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 1989-08-18)The "inappropriate" use of emergency departments (EDs) - for non urgent or minor ailments and high-frequency use, "heavy use" - is causing great concern to several Western countries, irrespective of differing health care ...