Licentiatavhandlingar / Licentiate Theses - C3 (FyFa)
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Recent submissions
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Circulating factors affecting skeletal muscle metabolism
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2024-05-21)The overall aim of this doctoral thesis was to study the role of circulating factors in modulating skeletal muscle metabolism. To this end, we investigated two different scenarios: Type 2 diabetes, which is characterised ... -
Patient and organisational perspectives of initial trauma care
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2018-10-18)Physical trauma is one of the major causes of death and disability worldwide. In Sweden a similar pattern can be seen despite having a well-organised health-care system. Improvements in trauma care can increase survival ... -
Sense of coherence (SOC) in women treated for breast cancer and its relation to treatment outcome
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2016-04-20)Breast cancer incidence has, on average increased by 1.4 % annually during the last decades. Early detection and advances in treatment are the main contributing factors for the favourable outcome in terms of five- and ... -
Influence of kynurenic acid on dopamine neurotransmission : implications for schizophrenia
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2015-03-26)Kynurenic acid (KYNA) belongs to the kynurenines, a group of metabolically related compounds derived from the amino acid tryptophan. It is an antagonist of glutamate- and α7 nicotinic acetylcholine (α7nACh) receptors. ... -
Limitations of maximal oxygen uptake during whole-body exercise
(Institutionen för fysiologi och farmakologi / Department of Physiology and Pharmacology, 2007-10-26)Oxygen uptake increases linearly with increased running speed or rate of work and finally reaches a maximum beyond which no effort can drive it further. This phenomenon is referred to as the plateau in oxygen uptake . ... -
Altering the fetal programming of the HPA axis and the consequences in the adult auditory system
(Institutionen för fysiologi och farmakologi / Department of Physiology and Pharmacology, 2006-11-16)Prenatal glueocorticoid (GC) has been associated with a variety of alterations in the adult offspring. Hypothalamo-Pituitary-Adrenal (HPA) axis, which is the key regulator for almost all kind of neuroendocine function and ... -
Exercise-induced mitochondrial biogenesis : with special reference to mitochondrial transcription factors and lipin-1
(Inst för fysiologi och farmakologi / Dept of Physiology and Pharmacology, 2012-11-22)Mitochondrial biogenesis is one prominent adaptation to endurance training in skeletal muscle tissue. An increased mitochondrial density of the muscle fibres contributes to an enhanced aerobic capacity and thereby to ... -
Procedure related pain and anxiety during bone marrow aspiration
(Institutionen för fysiologi och farmakologi / Department of Physiology and Pharmacology, 2010-04-14)Bone marrow aspiration/biopsy (BMA) is a common procedure used to diagnose and follow up treatment in patients with haematological disorders. Procedures in these patients are often associated with some pain, discomfort and ... -
Acute and early chronic responses to resistance exercise using flywheel or weights
(Institutionen för fysiologi och farmakologi / Department of Physiology and Pharmacology, 2008-05-15)Weight training typically offers constant external load during coupled shortening (concentric) and lengthening (eccentric) muscle actions in sets of consecutive repetitions until failure. However, skeletal muscle inherently ... -
Gene expression in human skeletal muscle : effects of activity, fibre type and inheritance for diabetes
(Institutionen för fysiologi och farmakologi / Department of Physiology and Pharmacology, 2006-04-07)One fundamental underlying risk factor for the development of non-insulin dependent (type 2) diabetes mellitus is insulin resistance, which 80-90% of all type 2 diabetic patients suffer from. Risk factors for insulin ...