RSS submission
 

Recent Submissions

  • Approaches to modulate vaccine-induced antibody responses 

    Soldemo, Martina (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-09-15)
    Most successful licensed vaccines mediate protection by inducing antibody responses capable of protecting the individual from infection or disease. Despite the availability of many effective vaccines, we lack knowledge ...
  • The atypical Rho GTPase RhoD and its role in cellular dynamics 

    Blom, Magdalena (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-24)
    Despite its discovery 20 years ago, the accumulated knowledge about the Rho member RhoD is scarce. Instead, the vast majority of studies concerning Rho GTPases has focused on the three classical members RhoA, Cdc42 and ...
  • Metabolism and neural differentiation in childhood neuroblastoma 

    Oliynyk, Ganna (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-19)
    Neuroblastoma is the most common and aggressive extracranial solid tumor during childhood. MYCN-amplification is found in approximately 25 % of all neuroblastoma cases, and is defined as high-risk disease. Development of ...
  • Immunity and immunological surveillance for malaria elimination in tropical islands 

    Md Idris, Zulkarnain (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-19)
    Malaria remains one of the most significant global public health challenges. Nearly half of the world’s population remains at risk, largely in African Region. In the past decade, considerable progress has been made in the ...
  • Natural killer cell education under conditions of perturbed sensing of MHC : studies in MHC-I mosaic and chimaeric mice 

    Salam, Sadia (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-19)
    Natural killer (NK) cells are innate lymphocytes that play a role in infections, tumours and transplantation. Their activating and inhibitory receptors sense cell surface ligands on potential target cells. Increased ...
  • Glycan-based interactions of Streptococcus pneumoniae and the host 

    Hentrich, Karina (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-17)
    Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or ...
  • Translational regulation in Plasmodium falciparum 

    Chan, Sherwin (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-12)
    Plasmodium falciparum is the causative agent of the most malignant form of human malaria, which remains as one of the most devastating infectious diseases. In face of a continuous international effort to eliminate the ...
  • The role of angiopoietin-like 4 in inflammation 

    Phua, Terri (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-05-04)
    Inflammation is a homeostatically fundamental feature of the host defence surveillance system made up of an army of sentinel cells that guard against foreign intrusion. At the onslaught of an attack, primary immune responders ...
  • Role of mitochondrial ribosomal protein S18-2 in cancerogenesis and in regulation of stemness and differentiation 

    Mushtaq, Muhammad (2017-05-02)
    Mitochondria carry their own ribosomes (mitoribosomes) for the translation of mRNA encoded by mitochondrial DNA. The architecture of mitoribosomes is mainly composed of mitochondrial ribosomal proteins (MRPs), which are ...
  • B cell fate following immunization : from memory B cells to plasma cells 

    Martínez Murillo, Paola (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-04-21)
    Most approved successful human vaccines induce neutralizing antibody titers maintained above a given threshold for long-term protection against potential pathogen exposure. The pathogens targeted by these vaccines are ...
  • Immune responses induced by immunization with HIV-1 DNA followed by HIV-modified vaccinia virus Ankara with or without recombinant GP140 in healthy Tanzanian individuals 

    Joachim, Agricola (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-04-18)
    A vaccine against HIV is widely considered the most effective and sustainable way of preventing new infections. We previously conducted a phase I/II clinical trial using multi-clade, multigene HIV-DNA priming and ...
  • The regulation of B cell responses in systemic autoimmunity 

    Duhlin, Amanda (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-04-10)
    Our immune system is a complex network made up of physical barriers and specialized proteins, cells and organs that all work together to prevent pathogens from causing disease in the body. Once the immune system has ...
  • Antigens and antibodies involved in humoral immunity to plasmodium falciparum 

    Wahlgren, Mats (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-03-31)
  • Dendritic cell migration to draining lymph node and T-cell priming to Bacille Calmette-Guérin 

    Bollampalli, Vishnu Priya (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-03-30)
    Dendritic cells (DCs) are unique antigen presenting cells that bridge innate and adaptive immunity. DCs sense invading microbes, sample antigen and migrate to the draining lymph node (DLN) where they prime T cells to the ...
  • CMV-infection in gay men with AIDS 

    Grützmeier, Sven (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-02-03)
    Background: Before the era of combination therapy (c-ART) more than 90 % of the patients with HIV-infection died of one or more opportunistic infections (OI). We and others noted early on that CMV was an important pathogen ...
  • Memory B-cell function and antibody profiles in malaria : their role in protection against disease in infancy 

    Lugaajju, Allan (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-02-02)
    Malaria infection is of huge public health importance in developing countries, including Uganda. Antibody immunity assumes a paramount part in the disease control however there’s a great need to study components of ...
  • Surface antigens in Plasmodium falciparum malaria : PfEMP1 and SURFIN4.2 

    Quintana Varon, Maria del Pilar (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2017-01-04)
    Plasmodium falciparum malaria is an infectious disease that on despite of the ongoing eradication efforts is still endemic in more than 100 countries, sometimes causing severe disease that leads to the death of around ...
  • Urinary tract infections in pregnancy : studies in vivo and in vitro 

    Sekikubo, Musa (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2016-11-09)
    The risk of urinary tract infection (UTI) in pregnant women is increased and predisposes them to acute pyelonephritis together with poor pregnancy outcomes. Increased frequency of micturition, nocturia and lower abdominal ...
  • Streptococcus pneumoniae and the host : activation, evasion and modulation of the human innate immune system 

    Spelmink, Laura (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2016-11-08)
    Streptococcus pneumoniae is a major cause of severe infections such as pneumonia, septicemia and meningitis, but also a common colonizer of the nasopharynx in children. In most individuals colonization is harmless and ...
  • Mechanisms of tumor microenvironment in promoting metastasis 

    Andersson, Patrik (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2016-11-07)
    Tumor tissues contain diverse cell populations that relentlessly cross-communicate with each other in the tumor microenvironment. In addition to malignant cells, infiltration of other host cells including inflammatory ...

View more