Studies on meniscus surgery with focus on preservation and meniscus function
Author: Rönnblad, Erik
Date: 2021-01-22
Location: Ejnar Lecture Hall, Capio Artro Clinic, Valhallavägen 91, Stockholm
Time: 09.00
Department: Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery
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Thesis (3.400Mb)
Abstract
The aim of this thesis was to investigate the effect of surgical preservation and restoration of the meniscus on knee function and outcomes. In Study I, 4497 patients with primary hamstring ACLR were evaluated regarding knee laxity preoperatively and at 6-months follow-up using KT-1000. The primary aim was to evaluate the ATT depending on type of treatment of meniscus injuries in conjunction to primary ACLR. A significant reduction in laxity was found for all patients. Medial meniscus resection resulted in significantly increased laxity compared to isolated ACLR. Medial meniscus repair resulted in laxity comparable to isolated ACLR. In Study II, all ACLRs from the SNKLR were evaluated. The primary aim was to compare KOOS and EQ-5D at 2-year follow-up after isolated ACLR to ACLR with associated meniscus injury treated with either repair or resection in the Swedish National Knee Ligament Register. Meniscus resection resulted in worse outcome, whereas meniscus repair resulted in comparable outcome to isolated ACLR. In Study III, 918 meniscus repairs were analysed. The primary aim was to assess failure within three years. Repair with arrows and medial repairs resulted in significantly more failures than repair with anchors and lateral repairs. Concomitant ACLR resulted in less failure of meniscus repair than isolated meniscus repairs. In Study IV, 316 consecutive meniscus repairs were followed up with radiology, KOOS and Lysholm. The primary aim was to determine the effect of meniscus repair on OA and secondly its effect on subjective knee function. Failed meniscus repair resulted in significantly higher risk for OA and worse patient reported outcome. In Study V, seven cases of meniscus transplantation using the semitendinosus tendon are described. The surgical technique is described in detail. Four patients had completed the 12- month follow-up and report significantly improved outcome in IKDC Global Score, KOOS pain subscale and Lysholm.
In conclusion, meniscus repair result in less OA and better subjective knee function than meniscus resection. Medial meniscus repair provides less knee laxity than meniscus resection. Failure after meniscus repair are more common for medial and isolated repairs. In cases of post meniscectomy symptoms, the semitendinosus tendon could possibly function as a meniscus transplant with improved knee function for the patients.
In conclusion, meniscus repair result in less OA and better subjective knee function than meniscus resection. Medial meniscus repair provides less knee laxity than meniscus resection. Failure after meniscus repair are more common for medial and isolated repairs. In cases of post meniscectomy symptoms, the semitendinosus tendon could possibly function as a meniscus transplant with improved knee function for the patients.
List of papers:
I. Medial Meniscus Resection Increases and Medial Meniscus Repair Preserves Anterior Knee Laxity: A Cohort Study of 4497 Patients with Primary Anterior Cruciate Ligament Reconstruction. R Cristiani, E Rönnblad, B Engström, M Forssblad, A Stålman. Am J Sports Med. 2018 Feb;46(2):357-362.
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II. Meniscus Repair With Simultaneous ACL Reconstruction Demonstrated Similar Clinical Outcomes as Isolated ACL Repair: a Result Not Seen With Meniscus Resection. M Phillips, E Rönnblad, L Lopez-Rengstig, E Svantesson, A Stålman, K Eriksson, O R Ayeni, K Samuelsson. Knee Surg Sports Traumatol Arthrosc. 2018 Aug;26(8):2270-2277.
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III. Predictive Factors for Failure of Meniscal Repair: A Retrospective Dual-Center Analysis of 918 Consecutive Cases. E Rönnblad, B Barenius, B Engström, K Eriksson. Orthop J Sports Med. 2020 Mar 27;8(3):2325967120905529.
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IV. Failed Meniscal Repair Increases the Risk for Osteoarhritis and Poor Knee Function at an Average of Nine Years Follow-up. E Rönnblad, B Barenius, A Stålman, K Eriksson. [Submitted]
V. Autologous Semitendinosus Tendon as Meniscal Transplant – a Pilot Study. E Rönnblad, P Rotzius, K Eriksson. [Manuscript]
I. Medial Meniscus Resection Increases and Medial Meniscus Repair Preserves Anterior Knee Laxity: A Cohort Study of 4497 Patients with Primary Anterior Cruciate Ligament Reconstruction. R Cristiani, E Rönnblad, B Engström, M Forssblad, A Stålman. Am J Sports Med. 2018 Feb;46(2):357-362.
Fulltext (DOI)
Pubmed
View record in Web of Science®
II. Meniscus Repair With Simultaneous ACL Reconstruction Demonstrated Similar Clinical Outcomes as Isolated ACL Repair: a Result Not Seen With Meniscus Resection. M Phillips, E Rönnblad, L Lopez-Rengstig, E Svantesson, A Stålman, K Eriksson, O R Ayeni, K Samuelsson. Knee Surg Sports Traumatol Arthrosc. 2018 Aug;26(8):2270-2277.
Fulltext (DOI)
Pubmed
View record in Web of Science®
III. Predictive Factors for Failure of Meniscal Repair: A Retrospective Dual-Center Analysis of 918 Consecutive Cases. E Rönnblad, B Barenius, B Engström, K Eriksson. Orthop J Sports Med. 2020 Mar 27;8(3):2325967120905529.
Fulltext (DOI)
Pubmed
View record in Web of Science®
IV. Failed Meniscal Repair Increases the Risk for Osteoarhritis and Poor Knee Function at an Average of Nine Years Follow-up. E Rönnblad, B Barenius, A Stålman, K Eriksson. [Submitted]
V. Autologous Semitendinosus Tendon as Meniscal Transplant – a Pilot Study. E Rönnblad, P Rotzius, K Eriksson. [Manuscript]
Institution: Karolinska Institutet
Supervisor: Eriksson, Karl
Co-supervisor: Barenius, Björn; Stålman, Anders; Engström, Björn
Issue date: 2020-12-23
Rights:
Publication year: 2020
ISBN: 978-91-8016-090-2
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