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  • TFAM forces mtDNA to make a U-turn 

    Hällberg, B. Martin; Nils-Göran, Larsson (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular BiologyInst för laboratoriemedicin / Dept of Laboratory MedicineMax Planck Institute for Biology of Ageing, Köln, Germany., 2014-08-04)
    The mammalian mitochondrial transcription factor A (TFAM) is encoded in the nucleus and imported into mitochondria, where it functions as an activator of mtDNA transcription and packages mtDNA into DNA-protein aggregates ...
  • Making proteins in the powerhouse 

    Hällberg, Martin; Larsson, Nils-Göran (Inst för laboratoriemedicin / Dept of Laboratory MedicineInst för cell- och molekylärbiologi / Dept of Cell and Molecular BiologyMax Planck Institute for Biology of Ageing, Cologne, Germany, 2014-08-04)
    Understanding regulation of mitochondrial DNA (mtDNA) expression is of considerable interest as mitochondrial dysfunction is important in human pathology and ageing. Similar to the situation in bacteria, there is no ...

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