Doktorsavhandlingar / Doctoral Theses - OF (OFA): Recent submissions
Now showing items 81-100 of 136
-
Oral mucositis and periodontal disease in patients with primary or acquired immunodeficiencies
(Inst för odontologi / Dept of Dental Medicine, 2013-09-11)The infection and inflammation in the oral cavity are commonly related to the skewed interaction between host immunity and inhabiting microorganisms. Both primary and acquired immunodeficiency conditions are frequently ... -
Surface roughness : causal factors and its relation to bacterial adhesion
(Inst för odontologi / Dept of Dental Medicine, 2013-05-24)Inflammation around teeth and dental implants is considered to be due to microorganisms producing biofilm and thereby initiating the inflammatory reaction. The etiology is not yet fully understood though many risk factors ... -
Inflammatory response in periodontal tissue in children with Down syndrome
(Inst för odontologi / Dept of Dental Medicine, 2013-05-15)Periodontal diseases are inflammatory diseases affecting the supporting tissues of the teeth. Subjects with Down syndrome have a higher prevalence of periodontal disease compared to healthy controls. Periodontal disease ... -
Health implications of dental amalgam
(Inst för odontologi / Dept of Dental Medicine, 2013-02-22)Dental amalgam is one of the most widely used, but also the most controversial of dental restorative materials. Since its introduction during the first half of the 19th century, concerns have been raised about health hazards ... -
Generation of polyfunctional T cells against HCV by T cell redirection and vaccination
(Inst för odontologi / Dept of Dental Medicine, 2012-11-21)The hepatitis C virus (HCV) is the major cause of liver disease and it is estimated that around 170 millions of people are infected worldwide. The available therapy is a combination of pegylated-interferon-alpha, ribavirin ... -
Oral health in children with juvenile idiopathic arthritis
(Inst för odontologi / Dept of Dental Medicine, 2012-11-12)The overall aim of this thesis was to illuminate different aspects of oral health that can be investigated in the clinical meeting with the child diagnosed with JIA. A cross-sectional case control study consisting ... -
Craniofacial bone tissue engineering with biomimetic constructs
(Inst för odontologi / Dept of Dental Medicine, 2012-10-29)The repair of bone defects and nonunions remains a significant clinical problem in orthopedic and maxillofacial reconstructive surgery. Tissue engineering offers a potential approach to overcome existing limitations related ... -
Genomic and dental investigations of individuals and families with non-syndromic cleft lip and/ or cleft palate, Van der Woude and popliteal pterygium syndromes
(Inst för odontologi / Dept of Dental Medicine, 2012-01-27)Van der Woude syndrome (VWS) is the most common oral cleft syndrome, accounting for two percent of all cleft lip and/or cleft palate (CL/P) cases. The main characteristics of VWS are lip pits (LP), cleft lip (CL), cleft ... -
Associations between oral biofilm, periodontal disease, and systemic health : with a focus on atherosclerosis and breast cancer
(Inst för odontologi / Dept of Dental Medicine, 2012-01-24)The general hypothesis of this series of studies was that oral infections, particularly periodontal disease, by triggering inflammatory reactions detrimentally affect systemic health where inflammations are known to play ... -
Dynamics of descending inhibition and neuroendocrine analgesia with special reference to the trigeminal region
(Inst för odontologi / Dept of Dental Medicine, 2011-11-25)In patients with pain, it is of relevance to use clinical assessments that evaluate the pain modulation. In this thesis, the dynamics of descending inhibition or central sensitization and neuroendocrine analgesia were ... -
Conditioning associated effects on oral mucosa and salivary function in allogeneic stem cell recipients
(Inst för odontologi / Dept of Dental Medicine, 2011-09-07)Allogeneic hematopoietic stem cell transplantation (HSCT) is an effective treatment for patients with a range of disorders of the immunohematopoietic system. In HSCT recipients, acute complications in the oral cavity are ... -
Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts
(Inst för odontologi / Dept of Dental Medicine, 2011-05-18)Periodontitis is a chronic inflammatory disease resulting in the destruction of the tissue and alveolar bone supporting the teeth and leading ultimately to tooth loss. Prostaglandin E2 (PGE2) is an important inflammatory ... -
Accuracy of virtually planned and CAD/CAM-guided dental implant surgery
(Inst för odontologi / Dept of Dental Medicine, 2011-04-20)The treatment with dental implants was introduced in the 1960s as an aid for patients who were missing teeth. Recently CAD/CAM guided surgical concepts have been launched on the market as a solution for treating single, ... -
Influence of deciduous canine extractions on incisor alignment, dental arch dimensions and dental fear
(Inst för odontologi / Dept of Dental Medicine, 2011-04-14)Interception of crowding, by extraction of deciduous and permanent teeth, to eliminate or at least facilitate orthodontic treatment has a long tradition. This treatment procedure, know as “guided eruption” or “serial ... -
Oral inflammatory conditions and diabetes mellitus
(Institutionen för odontologi / Department of Odontology, 2008-11-14)The association between periodontal inflammation and diabetes mellitus has been reported. However, the influence of hyperglycemia and gender in oral inflammation is still unclear. In this thesis, periodontal conditions ... -
Digital intraoral radiography : determination of technical properties and application evaluations
(Institutionen för odontologi / Department of Odontology, 2002-05-03)Digital registration of intraoral radiographs was introduced about 1990. One of the first systems on the market was the Sens-A-Ray (Regain Medical Systems AB, Sundsvall, Sweden). At the time of the introduction, it was ... -
Pain-related sodium channels in sensory neurons : gene expression during development and after injury
(Institutionen för odontologi / Department of Odontology, 2008-05-22)Pain that goes on over years as a result of nerve damage is an affliction which disables millions of people worldwide. Chronic injury-induced pain can become severely debilitating and extremely difficult to treat. ... -
Carbon-graphite fiber-reinforced polymers for implant suprastructures
(Institutionen för odontologi / Department of Odontology, 2009-04-03)Carbon-graphite fiber-reinforced polymers (CGFR) can be used as the core material for implant-retained prostheses as an alternative to metal frameworks. The purpose was to formulate and develop carbon-graphite fiber-reinforced ... -
Glutamate modulates temporomandibular joint bone tissue resorption in patients with early rheumatoid arthritis
(Institutionen för odontologi / Department of Odontology, 2010-10-01)The general aim was to investigate the occurrence and development of TMJ bone tissue resorption and to identify predictors for progression during the two first years with rheumatoid arthritis. The thesis comprises ... -
Expression and regulation of MMP-1 and MMP-3 in human gingival fibroblasts
(Institutionen för odontologi / Department of Odontology, 2005-11-11)Matrix metalloproteinases (MMPs) are a group of proteolytic enzymes collectively responsible for the metabolism of extra cellular matrix components. Disturbance of the physiological balance between MMPs and their endogenous ...