Inst för odontologi / Dept of Dental Medicine: Recent submissions
Now showing items 1-20 of 131
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Studies on molecular and immune signatures for detection of pancreatic cancer and COVID-19
(Inst för odontologi / Dept of Dental Medicine, 2021-05-19)Background and objectives Etiological factors and accurate diagnostic biomarkers have remained elusive to pancreatic cancer, a disease with > 90% five-years mortality rate. The recent understanding of microbiome interaction ... -
Gateway to the gut : alterations in saliva in inflammatory bowel disease
(Inst för odontologi / Dept of Dental Medicine, 2021-05-12)Inflammatory bowel disease (IBD), which consists of Crohn’s disease and ulcerative colitis, is a chronic immune-mediated disease thought to result from genetic and environmental interaction which influence the commensal ... -
Mastication in jaw muscle pain
(Inst för odontologi / Dept of Dental Medicine, 2021-05-12)Background: Integrated Pain Adaptation Models suggest a possible pain-motor interaction. Mechanisms affecting the jaw muscle spindles seem to affect the ability to bite and chew, suggesting that jaw muscle pain may be a ... -
Expression of biomarkers by peripheral nerve fibres in human masseter muscle
(Inst för odontologi / Dept of Dental Medicine, 2021-01-27)Background: Temporomandibular disorders (TMDs) often manifest as masticatory muscle pain (myalgia). Nerve growth factor (NGF) and glutamate injection into healthy human masseter muscle induced signs and symptoms mimicking ... -
The orofacial cleft phenome
(Inst för odontologi / Dept of Dental Medicine, 2020-12-29)Introduction: The global average for prevalence in births with orofacial clefts is 9.92 per 10,000. Variability in prevalence could be as much as a seven-fold difference in different ethnicities. Precise phenotyping and ... -
Biting and chewing behaviours in humans : development and age-related changes
(Inst för odontologi / Dept of Dental Medicine, 2020-10-09)Background: The central nervous system initiates chewing and biting behaviours, while the peripheral sensory receptors embedded in various orofacial structures (e.g. masticatory muscles, temporomandibular joint, and ... -
Biomarkers and surgical predictors in temporomandibular joint disease
(Inst för odontologi / Dept of Dental Medicine, 2020-09-07)Background: Temporomandibular joint (TMJ) disc displacement (DD) is associated with pain and impaired function and has two main sub-diagnoses, DD with or without reduction (DDwR/DDwoR). DD synovial tissue has been sparsely ... -
Studies on myeloid cell functions in periodontitis
(Inst för odontologi / Dept of Dental Medicine, 2020-08-05)Periodontitis (PD) is a chronic inflammatory disease characterized by destruction of the tooth supporting tissues; gingiva, periodontal ligament, and alveolar bone. Myeloid cells, including monocytes and macrophages, play ... -
Extensive tooth wear in adults : classification and prosthetic treatment
(Inst för odontologi / Dept of Dental Medicine, 2020-05-27)Background: Tooth wear (TW) is an insidious and cumulative mul- tifactorial process that may comprise erosion, abrasion or attrition, and combinations thereof. These different processes are of chemical or physical origin ... -
Salivary biomarkers in chronic muscle pain
(Inst för odontologi / Dept of Dental Medicine, 2020-05-07)Background: Muscle related temporomandibular disorders (TMD myalgia), one of the most common orofacial pain conditions, is characterized by facial pain and often accompanied by jaw movement limitations. Although the ... -
Evaluation of cone beam computed tomography with respect to effective radiation dose and diagnostic properties
(Inst för odontologi / Dept of Dental Medicine, 2020-01-30)Cone beam computed tomography (CBCT) is an x-ray modality providing three-dimensional x-ray images. CBCT devices have high resolution compared to traditional medical CT, making them suitable for examination of fine details. ... -
Clinical, microbiological and immunological effects of antiseptics in periodontal treatment
(Inst för odontologi / Dept of Dental Medicine, 2019-12-19)Periodontal diseases are characterized by high prevalence in many populations and the chronic and progressive course of the disease. A fundamental stage of treatment is mechanical debridement of the tooth surface. During ... -
Periodontitis and invasive oral treatment in relation to myocardial infarction : epidemiological studies
(Inst för odontologi / Dept of Dental Medicine, 2019-11-25)Background: Cardiovascular disease and periodontitis are major global health problems that are a large burden for the individual and society. During the last 30 years, it has been discussed whether there is an association ... -
Craniofacial development after three different palatoplasties in children born with isolated cleft palate
(Inst för odontologi / Dept of Dental Medicine, 2018-11-14)Introduction: Different palatoplasties are applied for the surgical correction of children born with an isolated cleft in the palate (ICP). During the last decades the Veau-Wardill-Kilner (VWK), Minimal Incision (MI) and ... -
Periodontal medicine : oral inflammatory conditions with special emphasis on immunological aspects
(Inst för odontologi / Dept of Dental Medicine, 2018-11-07)Systemic effects of periodontal disease have been a subject of interest for the past century, with intense focus converging since the past decade. Both rheumatoid arthritis (RA) and periodontal disease (PD) are immuno-inflammatory ... -
Periodontal implications of Salvadora persica L.
(Inst för odontologi / Dept of Dental Medicine, 2018-11-02)Periodontal disease is a major public health problem throughout the world and is the most common cause of tooth loss in adults. For periodontitis to develop, specific gram-negative, anaerobic bacteria must predominate in ... -
Jaw exercises in the treatment of masticatory myofascial pain : efficacy, patients’ views and dentists’ experiences
(Inst för odontologi / Dept of Dental Medicine, 2018-08-27)The main aim of this thesis was to gain better knowledge concerning different aspects of jaw exercises in the treatment of masticatory myofascial pain. Special emphasis was directed towards efficacy and cost-effectiveness ... -
Prevalence of dentinogenesis imperfecta and dental aberrations related to genetic findings in osteogenesis imperfecta
(Inst för odontologi / Dept of Dental Medicine, 2018-05-04)Osteogenesis imperfecta (OI) is a clinically and genetically heterogeneous connective tissue disorder, mainly caused by mutations in COL1A1 and COL1A2, the genes encoding collagen type I. The cardinal symptoms include bone ... -
Diagnostic criteria and dose limiting approaches for image modalities in odontology
(Inst för odontologi / Dept of Dental Medicine, 2018-03-21)Objectives: Technical innovations in radiography enable the development of new approaches to reduce the dose to patients. The aim of this thesis was to explore dose optimization approaches for the most frequently used ... -
Tooth loss and prosthetic replacements among persons with dependency and functional limitations
(Inst för odontologi / Dept of Dental Medicine, 2018-01-24)The overall aim of this thesis was to obtain a decision basis for assessments and planning regarding prosthetic treatments for persons with dependency and functional limitations. For this purpose the epidemiology of tooth ...