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  • Looking for arthritis regulating genes on mouse chromosome 6 & 14 

    Popovic, Marjan (Institutionen för medicinsk biokemi och biofysik (MBB) / Department of Medical Biochemistry and Biophysics, 2008-11-05)
    Rheumatoid arthritis (RA) is a chronic autoimmune disease of the joints with a complex aetiology affected by largely unknown genetic and environmental factors. Because ~60% of susceptibility to RA is genetically inherited, ...
  • Biosynthesis and biological role of leukotrienes in B lymphocytes 

    Mahshid, Yilmaz (Institutionen för medicinsk biokemi och biofysik (MBB) / Department of Medical Biochemistry and Biophysics, 2006-11-27)
    Leukotrienes (LT) are potent lipid mediators, synthesized from arachidonic acid (AA) upon cell activation. The essential enzyme for leukotriene biosynthesis is 5-lipoxygenase (5-LO), converting AA, through a two step process ...

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