Doktorsavhandlingar / Doctoral Theses: Recent submissions

Now showing items 1-20 of 9296

    • Delineating cell types and toxicity in human ovaries from birth to sexual maturity 

      Hassan, Jasmin (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-05-06)
      The ovary contains the female germ cells known as oocytes, which are essential for female fertility. The immature oocytes reside within primordial follicles in the ovarian cortex and are referred to as the ovarian reserve. ...

    • Pyrocarbon in shoulder hemi arthroplasty 

      Hallberg, Kristofer (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-05-03)
      Pyrolytic carbon, or pyrocarbon (PyC), has biocompatibility, a low friction coefficient and good wear resistance, making it a material of great potential for use in orthopaedics. PyC shoulder implants have shown promising ...

    • Diet, genetic susceptibility, latent autoimmune diabetes in adults, type 1 and type 2 diabetes 

      Lampousi, Anna-Maria (Institutet för miljömedicin / Institute of Environmental Medicine, 2024-05-03)
      Diabetes is one of the most common chronic diseases, yet our understanding of modifiable risk factors remains incomplete. This project aimed to elucidate the role of diet in the risk of latent autoimmune diabetes in adults ...

    • Hepatic diseases at the molecular level : identifying novel targets and biomarkers through transcriptomics 

      Sommerauer, Christian (Inst för mikrobiologi, tumör- och cellbiologi / Dept of Microbiology, Tumor and Cell Biology, 2024-05-03)
      In the last few decades, the prevalence of obesity and metabolic diseases have dramatically increased and pose a major threat to global healthcare systems. The chronic excess of carbohydrates and fat is a risk factor for ...

    • Mortality prediction and equity in emergency care 

      Malmer, Gustav (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-05-03)
      Introduction: Emergency departments (EDs) face crowding and long patient waiting times due to resource-demand imbalances. Waiting exposes patients to sufferings and risks, such as pain, anxiety, permanent organ damage, or ...

    • Impact of non-health sector determinants on child health the role of the Sustainable Development Goals : models, practices and perceptions in Cambodia and globally 

      Helldén, Daniel (Inst för global folkhälsa / Dept of Global Public Health, 2024-05-02)
      Background. Child health has improved significantly over the last decades in Cambodia and globally. With the global adoption of the Sustainable Development Goals (SDGs) in 2015, a broad set of interlinked global goals to ...

    • Surgical treatment of lung cancer 

      Sachs, Erik (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-05-02)
      Background: Surgery is a central part in the treatment of lung cancer. There have been recent advances in minimal invasive and lung sparing surgical techniques, but evidence regarding safety and implementability is not ...

    • Automated microfluidic-based production of PET radioligands for clinical and preclinical use 

      Mallapura, Hemantha (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-05-02)
      In recent decades, microfluidic technologies have been explored for PET radiopharmaceutical production. Moreover, radiotracer production models have been gradually transitioning from centralized to decentralized models ...

    • Sexual health in young adult survivors of childhood cancer : prevalence, predictors and web-based support 

      Fagerkvist, Kristina (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-05-02)
      Aim: The overall aim of this thesis was to investigate the prevalence of sexual activity and dysfunction in young adult survivors (19-40 years) of childhood cancer in comparison to the general population. A further aim was ...

    • Exposures through drinking water and risk of chronic disease 

      Helte, Emilie (Institutet för miljömedicin / Institute of Environmental Medicine, 2024-05-02)
      Drinking water is the most important constituent of our diet. Yet, the importance of drinking water quality for population health is understudied. The overall aim of this thesis was to increase this knowledge by examining ...

    • Exploring allergic and irritant contact dermatitis : biomarkers, mechanisms, and allergen uptake 

      Werner Nosrati, Paulina (Institutet för miljömedicin / Institute of Environmental Medicine, 2024-04-30)
      Contact dermatitis (CD) is a common disease resulting from direct skin contact with allergens or irritants and greatly affects the life quality of suffering individuals. It is categorized into two main forms, namely allergic ...

    • Immune responses after SARS-CoV-2 infection and/or vaccination 

      Havervall, Sebastian (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-04-30)
      From the start of the COVID-19 pandemic, it was clear that studying immune responses after SARS-CoV-2 infection and later on, after vaccination, was of outmost importance in battling the pandemic. To understand immunological ...

    • Neuromuscular electrical stimulation in physical inactivity 

      Flodin, Johanna (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-04-30)
      Physical inactivity and immobilization have emerged as major health issues. Neuromuscular electrical stimulation (NMES) is a potential treatment to prevent the negative effects of physical inactivity, such as muscle atrophy ...

    • Catheter ablation of atrial fibrillation : methods for improving outcome 

      Paul Nordin, Astrid (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2024-04-30)
      Introduction: The most common arrhythmia world-wide is atrial fibrillation (AF). The arrhythmia is diagnosed through an electrocardiogram (ECG). Patients with AF often experience symptoms including palpitations, dyspnoea, ...

    • Volumetric and cortical brain development and outcome in children born extremely preterm 

      Kvanta, Hedvig (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-04-30)
      Children born extremely preterm (EPT) survive at an increasing rate. But they continue to have an increased risk for neurodevelopmental impairments. Magnetic resonance imaging (MRI) is used in a clinical setting, but can ...

    • Psychological self-care in chronic conditions : development of digital interventions in type 1 diabetes and atopic dermatitis 

      Kern, Dorian (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-04-30)
      Background: Psychological interventions for somatic conditions have a long history with many successful examples, often based on cognitive behavioural therapy (CBT) However, psychologists are not commonly found in somatic ...

    • Molecular and functional organization of the locomotor networks : from brainstem to spinal cord 

      Maëlle, Bertho (Inst för neurovetenskap / Dept of Neuroscience, 2024-04-30)
      Locomotion is a complex behavior that allows us to move and interact with the surroundings. In mammals, descending locomotor commands from the brainstem act directly onto spinal locomotor circuits to initiate or halt ...

    • Neurocomputational modelling of human decision making and volition : from neural mechanisms to behavioral outcomes 

      Hassannejad Nazir, Azadeh (Inst för neurovetenskap / Dept of Neuroscience, 2024-04-30)
      In today's world, amidst the bombardment of information, the mental health and well-being of a society with higher level of responsibility hinge on a central issue related to decision making and human agency. The essence ...

    • Advancing cardiovascular shear wave elastography and image registration : method development and safety evaluation 

      Nordenfur, Tim (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-04-29)
      Cardiovascular disease remains the leading cause of death and disability worldwide, with its burden on health and healthcare systems projected to rise. In cardiovascular diagnostics and treatment strategy decisions, medical ...

    • Innovations in pancreatology 

      Asif, Halimi (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-04-26)
      In paper I, we explored the presence and potential significance of intracystic pancreatic microbiomes in patients with suspected pancreatic cystic neoplasms (PCNs), who underwent pancreatic surgery. Paired samples of ...