Now showing items 21-40 of 395

    • Maternal asthma and early fetal growth : the MAESTRO study 

      Rejnö, Gustaf; Lundholm, Cecilia; Saltvedt, Sissel; Larsson, Kjell; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-02-08)
      Background: Several maternal conditions can affect fetal growth, and asthma during pregnancy is known to be associated with lower birth weight and shorter gestational age. Objective: In a new Swedish cohort study ...
    • Paediatric asthma and non-allergic comorbidities : a review of current risk and proposed mechanisms 

      Brew, Bronwyn K; Osvald, Emma Caffrey; Gong, Tong; Hedman, Anna M; Holmberg, Kirsten; Larsson, Henrik; Ludvigsson, Jonas F; Mubanga, Mwenya; Smew, Awad I; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-24)
      It is increasingly recognized that children with asthma are at a higher risk of other non-allergic concurrent diseases than the non-asthma population. A plethora of recent research has reported on these comorbidities and ...
    • Season of birth, childhood asthma and allergy in a nationwide cohort : mediation through lower respiratory infections 

      Almqvist, Catarina; Ekberg, Sara; Rhedin, Samuel; Fang, Fang; Fall, Tove; Lundholm, Cecilia (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-23)
      Background: Previous studies have suggested an association between season of birth and risk of childhood asthma and allergic disease. The association may be modified by birth year and region, or mediated by respiratory ...
    • Risk and predictors of out-of-home care placement among children and adolescents with parental mental illness : a population-based cohort study in Sweden (Study IV) 

      Nevriana, Alicia (Inst för global folkhälsa / Dept of Global Public Health, 2023-01-17)
      Here, we propose a nationwide population-based study on predictors of out-of-home care placement among children of mentally ill parents, using rich information from Swedish national health and administrative registers. We ...
    • Understanding the relationship between asthma and autism spectrum disorder : a population-based family and twin study 

      Gong, Tong; Lundholm, Cecilia; Lundström, Sebastian; Kuja-Halkola, Ralf; Taylor, Mark; Almqvist, Catarina (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-17)
      Background: There is some evidence that autism spectrum disorder (ASD) frequently co-occurs with immune-mediated conditions including asthma. We aimed to explore the familial co-aggregation of ASD and asthma using different ...
    • Limited association between markers of stress during pregnancy and fetal growth in 'Born into Life' : a new prospective birth cohort 

      Smew, Awad I; Hedman, Anna M; Chiesa, Flaminia; Ullemar, Vilhelmina; Andolf, Ellika; Pershagen, Göran; Almqvist, Catarina (Institutet för miljömedicin / Institute of Environmental MedicineInst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and BiostatisticsInst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2023-01-17)
      Aims: We aimed to investigate the associations between perceived maternal stress or salivary cortisol levels during pregnancy and birthweight. Methods: In 2010-2012, we recruited 92 women living in Stockholm, Sweden, ...
    • Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles 

      Gupta, Dhanu; Wiklander, Oscar P B; Görgens, André; Conceição, Mariana; Corso, Giulia; Liang, Xiuming; Seow, Yiqi; Balusu, Sriram; Feldin, Ulrika; Bostancioglu, Beklem; Jawad, Rim; Mamand, Doste R; Lee, Yi Xin Fiona; Hean, Justin; Mäger, Imre; Roberts, Thomas C; Gustafsson, Manuela; Mohammad, Dara K; Sork, Helena; Backlund, Alexandra; Lundin, Per; de Fougerolles, Antonin; Smith, C I Edvard; Wood, Matthew J A; Vandenbroucke, Roosmarijn E; Nordin, Joel Z; El-Andaloussi, Samir (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2022-12-06)
      Extracellular vesicles (EVs) can be functionalized to display specific protein receptors on their surface. However, surface-display technology typically labels only a small fraction of the EV population. Here, we show that ...
    • Visuo-thermal congruency modulates the sense of body ownership 

      Crucianelli, Laura; Ehrsson, H Henrik (Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)
      Thermosensation has been redefined as an interoceptive modality that provides information about the homeostatic state of the body. However, the contribution of thermosensory signals to the sense of body ownership remains ...
    • Limits of cross-modal plasticity? Short-term visual deprivation does not enhance cardiac interoception, thermosensation, or tactile spatial acuity 

      Radziun, Dominika; Crucianelli, Laura; Ehrsson, H Henrik (Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)
      In the present study, we investigated the effect of short-term visual deprivation on discriminative touch, cardiac interoception, and thermosensation by asking 64 healthy volunteers to perform four behavioral tasks. The ...
    • Editorial : When the body feels like mine : constructing and deconstructing the sense of body ownership through the lifespan 

      Crucianelli, Laura; Cascio, Carissa J; Salomon, Roy; Salvato, Gerardo (Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)
    • Interoception as independent cardiac, thermosensory, nociceptive, and affective touch perceptual submodalities 

      Crucianelli, Laura; Enmalm, Adam; Ehrsson, H Henrik (Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)
      Interoception includes signals from inner organs and thin afferents in the skin, providing information about the body’s physiological state. However, the functional relationships between interoceptive submodalities are ...
    • The role of the skin in interoception : a neglected organ? 

      Crucianelli, Laura; Ehrsson, H Henrik (Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)
      In the past two decades, interoception has received increasing attention in the fields of psychology and cognitive science, as well as neuroscience and physiology. A plethora of studies adopted the perception of cardiac ...
    • Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function 

      Michel, Maurice; Benitez-Buelga, Carlos; Calvo, Patricia A; Hanna, Bishoy M F; Mortusewicz, Oliver; Masuyer, Geoffrey; Davies, Jonathan; Wallner, Olov; Sanjiv, Kumar; Albers, Julian J; Castaneda-Zegarra, Sergio; Jemth, Ann-Sofie; Visnes, Torkild; Saste-Perona, Ana; Danda, Akhilesh N; Homan, Evert J; Marimuthu, Kartrick; Zhenjun, Zhao; Chi, Celestine N; Sarno, Antonio; Wiita, Elisee; von Nicolai, Catharina; Komor, Anna J; Rajagopal, Varshni; Müller, Sarah; Hank, Emily C; Varga, Marek; Scaletti, Emma R; Pandey, Monica; Karsten, Stella; Haslene-Hox, Hanne; Loevenich, Simon; Marttila, Petra; Rasti, Azita; Mamonov, Kirill; Ortis, Florian; Schömberg, Fritz; Loseva, Olga; Stewart, Josephine; D'Arcy-Evans, Nicholas; Koolmeister, Tobias; Henriksson, Martin; Michel, Dana; de Ory, Ana; Acero, Lucia; Calvete, Oriol; Scobie, Martin; Hertweck, Christian; Vilotijevic, Ivan; Kalderén, Christina; Osorio, Ana; Perona, Rosario; Stolz, Alexandra; Stenmark, Pal; Warpman Berglund, Ulrika; de Vega, Miguel; Helleday, Thomas (Inst för onkologi-patologi / Dept of Oncology-Pathology, 2022-08-19)
      Oxidative DNA damage is recognised by 8-oxoguanine (8-oxoG) DNA glycosylase 1 (OGG1), which excises 8-oxoG, leaving a substrate for apurinic endonuclease 1 (APE1), initiating repair. Here, we describe a small molecule ...
    • Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure 

      De Genst, Erwin; Foo, Kylie S; Xiao, Yao; Rohner, Eduarde; de Vries, Emma; Sohlmér, Jesper; Witman, Nevin; Hidalgo, Alejandro; Kolstad, Terje R S; Louch, William E; Pehrsson, Susanne; Park, Andrew; Ikeda, Yasuhiro; Li, Xidan; Mayr, Lorenz M; Wickson, Kate; Jennbacken, Karin; Hansson, Kenny; Fritsche-Danielson, Regina; Hunt, James; Chien, Kenneth R (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2022-08-19)
      The dysregulated physical interaction between two intracellular membrane proteins, the sarco/endoplasmic reticulum Ca2+ ATPase and its reversible inhibitor phospholamban, induces heart failure by inhibiting calcium cycling. ...
    • An mRNA assay system demonstrates proteasomal-specific degradation contributes to cardiomyopathic phospholamban null mutation 

      Rohner, Eduarde; Witman, Nevin; Sohlmér, Jesper; De Genst, Erwin; Louch, William E; Sahara, Makoto; Chien, Kenneth R (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2022-08-17)
      Background: The human L39X phospholamban (PLN) cardiomyopathic mutant has previously been reported as a null mutation but the detailed molecular pathways that lead to the complete lack of detectable protein remain to be ...
    • Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors 

      Poch, Christine M; Foo, Kylie S; De Angelis, Maria Teresa; Jennbacken, Karin; Santamaria, Gianluca; Bähr, Andrea; Wang, Qing-Dong; Reiter, Franziska; Hornaschewitz, Nadja; Zawada, Dorota; Bozoglu, Tarik; My, Ilaria; Meier, Anna; Dorn, Tatjana; Hege, Simon; Lehtinen, Miia L; Tsoi, Yat Long; Hovdal, Daniel; Hyllner, Johan; Schwarz, Sascha; Sudhop, Stefanie; Jurisch, Victoria; Sini, Marcella; Fellows, Mick D; Cummings, Matthew; Clarke, Jonathan; Baptista, Ricardo; Eroglu, Elif; Wolf, Eckhard; Klymiuk, Nikolai; Lu, Kun; Tomasi, Roland; Dendorfer, Andreas; Gaspari, Marco; Parrotta, Elvira; Cuda, Giovanni; Krane, Markus; Sinnecker, Daniel; Hoppmann, Petra; Kupatt, Christian; Fritsche-Danielson, Regina; Moretti, Alessandra; Chien, Kenneth R; Laugwitz, Karl-Ludwig (Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2022-08-02)
      Heart regeneration is an unmet clinical need, hampered by limited renewal of adult cardiomyocytes and fibrotic scarring. Pluripotent stem cell-based strategies are emerging, but unravelling cellular dynamics of host–graft ...
    • Cadmium intake as a prognostic factor in endometrial cancer : a Swedish cohort-based study 

      Razumova, Zoia; Govorov, Igor; Östensson, Ellinor; Mints, Miriam (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-22)
      Metalloendocrinology is a new interdisciplinary field, which was established due to the importance of connections between inorganic chemicals and hormonal mechanisms. The role of cadmium in hormone-related tumors is an ...
    • The prognostic role of LRIG proteins in endometrial cancer 

      Razumova, Zoia; Oda, Husam; Govorov, Igor; Lundin, Eva; Östensson, Ellinor; Lindquist, David; Mints, Miriam (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-22)
      Endometrial cancer (EC) is the most common gynecologic malignancy in Sweden and it has various prognostic factors. The LRIG family is a group of three integral surface proteins with a similar domain organization. The ...
    • Contrast-enhanced ultrasound is useful for the evaluation of focal liver lesions in children 

      Torres, Alvaro; Koskinen, Seppo K; Gjertsen, Henrik; Fischler, Björn (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-28)
      Introduction: Contrast-enhanced ultrasound (CEUS) is a widely used diagnostic method. In adults, it has been proven to be a useful alternative to CT and MRI for the characterisation of focal liver lesions (FLLs). However, ...
    • Contrast-enhanced ultrasound for identifying circulatory complications after liver transplants in children 

      Torres, Alvaro; Koskinen, Seppo K; Gjertsen, Henrik; Fischler, Björn (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-28)
      Our main goal with this study was to share our off-label experience with CEUS for identifying circulatory complications after liver transplantation in children. A total of 74 CEUS examinations performed on 34 pediatric ...