Now showing items 41-60 of 9496

    • Am I mad, bad or dangerous? A novel intervention approach for unwanted intrusive thoughts 

      Olofsdotter Lauri, Klara (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-02-14)
      Background: Unwanted intrusive thoughts (UITs) containing unacceptable and taboo themes is regarded as a common and, for most, transient cognitive phenomenon. However, these thoughts can become so frequent and distressing ...
    • Consumer reported digital immunization records : feasibility, applicability, and public health utility in the Canadian context 

      Atkinson, Katherine M (Inst för global folkhälsa / Dept of Global Public Health, 2024-02-13)
      Background: Vaccination is one of the most effective public health interventions of all time. Public health programs collect data on Vaccination Coverage (VC) to determine levels of protection and guide resource allocation ...
    • Parkinson's disease and Gaucher disease : focus on the GBA1 link 

      Brodin, Lovisa (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-02-13)
      Parkinson’s disease (PD) is the 2nd most common neurodegenerative disorder in the world, characterized by both motor as well as many non-motor features. There are many symptomatic treatments available, that may shift ...
    • Enhancing the efficiency of viral and non-viral gene delivery vectors 

      Bazaz, Safa (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2024-02-13)
      Gene therapy, which involves the introduction, alteration, or deletion of genetic material within cells to treat or prevent disease, holds great promise for addressing various genetic disorders and other medical conditions. ...
    • Does online parent training measure up to group parent training in real-world settings? 

      Engelbrektsson, Johanna (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-02-12)
      Background: Disruptive behavior problems involve recurrent patterns of defiance, aggression, and hostility that interfere with normal functioning. Disruptive behaviors are commonly observed in children and adolescents and ...
    • Targeting the ovary : mapping mechanisms to link endocrine-disrupting chemicals to female fertility 

      Li, Tianyi (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2024-02-09)
      In recent decades, growing attention has been paid to endocrine-disrupting chemicals (EDCs) as mounting evidence suggests that they can cause detrimental reproductive outcomes in animals and humans. Even though epidemiological ...
    • The efficacy of continuous peripheral blocks after cardiothoracic surgery as evaluated by opioid use, pain, and recovery 

      Larsson, Mark (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-02-09)
      Pain after cardiothoracic surgery is most intense the first postoperative days and for the most part mild to moderate. International guidelines recommend a multimodal analgesic strategy that includes local anesthetics for ...
    • Vacuum extraction and pelvic floor injury : a randomized controlled trial and cohort studies 

      Bergendahl, Sandra (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-02-06)
      BACKGROUND AND AIMS: Pelvic floor dysfunction (PFD) affects many women, especially after complicated childbirth. The impact of a prolonged second stage on PFD is not clear, while the effects of operative vaginal birth (OVB) ...
    • Organic electronics and microphysiological systems to interface, monitor, and model biology 

      Buchmann, Sebastian (Inst för neurovetenskap / Dept of Neuroscience, 2024-02-06)
      Biological processes in the human body are regulated through complex and precise arrangements of cell structures and their interactions. In vivo models serve as the most accurate choice for biological studies to understand ...
    • Clinical characteristics and treatment outcomes in body dysmorphic disorder 

      Rautio, Daniel (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-02-01)
      Body dysmorphic disorder (BDD) is an early onset mental disorder characterized by a preoccupation with perceived flaws in physical appearance. Research on the presentation of the disorder is sparse, especially on young ...
    • Cardiovascular magnetic resonance evaluation of effusive and constrictive physiologies 

      Thalén, Simon Olof Anders (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-01-31)
      This thesis presents an exploration of cardiovascular magnetic resonance (CMR) in the evaluation of effusive and constrictive heart conditions. Central to the thesis is advanced CMR as a diagnostic tool in pericardial ...
    • Alcohol consumption and cognition 

      Tsevis, Theofanis (Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2024-01-31)
      There is evidence that alcohol consumption is increasing in recent decades, including both male and female older individuals. Excessive alcohol use can affect various functions, of which alcohol-related liver failure and ...
    • Understanding juvenile idiopathic arthritis : a multidimensional approach 

      Saleh, Raya (Inst för medicin, Solna / Dept of Medicine, Solna, 2024-01-25)
      The overarching objective of this doctoral thesis is to enhance the understanding of Juvenile Idiopathic Arthritis (JIA), a complex autoimmune disease affecting children. With the aim of filling the knowledge gaps in JIA, ...
    • Monitoring of the oral anticoagulants apixaban and rivaroxaban to optimize individual safety and efficacy 

      Al-Aieshy, Fadiea (Inst för medicin, Solna / Dept of Medicine, Solna, 2024-01-25)
      The oral anticoagulants apixaban and rivaroxaban are administered at fixed doses without requiring routine monitoring. However, there is a dose and exposure dependency in efficacy and safety, and monitoring the anticoagulants ...
    • Visual perception in infancy and its links to later autism 

      Hardiansyah, Irzam (Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2024-01-24)
      Alterations in primary sensory areas of the brain have been suggested to be at the roots of the well-documented visual perceptual differences in autism. However, despite the possible key role these sensory processing ...
    • Apolipoprotein CIII in the pathophysiology of diabetes mellitus 

      Recio López, Patricia (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-01-24)
      It has previously been shown that high levels of apolipoprotein CIII (apoCIII) are related to both type-1 (T1D) and type-2 diabetes (T2D). In this thesis, mechanisms whereby apoCIII affects diet- and genetically-induced ...
    • Proximal hamstring avulsions : surgery or not? 

      Pihl, Elsa (Inst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2024-01-24)
      In paper 1, a retrospective cohort study of patients treated for proximal hamstring avulsions at Danderyd Hospital from 2007–2013 was conducted. The study was performed in 2015. The primary outcome was the subjective patient ...
    • Multimodal and multiscale brain networks : understanding aging, Alzheimer’s disease, and other neurodegenerative disorders 

      Canal Garcia, Anna (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2024-01-24)
      The human brain can be modeled as a complex network, often referred to as the connectome, where structural and functional connections govern its organization. Several neuroimaging studies have focused on understanding the ...
    • Comorbidities in early rheumatoid arthritis 

      Tidblad, Liselotte (Inst för medicin, Solna / Dept of Medicine, Solna, 2024-01-23)
      All of the studies that form part of this thesis concern the subject of comorbid conditions in early rheumatoid arthritis (RA). We have used linkage of Swedish clinical and demographic registers as well as the Swedish ...
    • Prostate cancer : investigating diagnosis, treatment and outcomes 

      Möller, Axel (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2024-01-19)
      Background: Prostate cancer is difficult to study. The prostate is located so that it is hard to palpate and because of the dense pelvic bones it is hard to visualize using radiology such as computed tomography. The prostate ...