Artiklar / Articles - K6 (KBH)
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Recent submissions
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MicroRNA-210 regulates dendritic morphology and behavioural flexibility in mice
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2023-08-16)MicroRNAs are known to be critical regulators of neuronal plasticity. The highly-conserved, hypoxia- regulated microRNA-210 (miR-210) has been shown to be associated with long term memory in invertebrates and dysregulated ... -
Cadmium intake as a prognostic factor in endometrial cancer : a Swedish cohort-based study
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-22)Metalloendocrinology is a new interdisciplinary field, which was established due to the importance of connections between inorganic chemicals and hormonal mechanisms. The role of cadmium in hormone-related tumors is an ... -
The prognostic role of LRIG proteins in endometrial cancer
(Inst för kvinnors och barns hälsa / Dept of Women's and Children's Health, 2022-04-22)Endometrial cancer (EC) is the most common gynecologic malignancy in Sweden and it has various prognostic factors. The LRIG family is a group of three integral surface proteins with a similar domain organization. The ... -
Number of siblings and survival from childhood leukaemia : a national register-based cohort study from Sweden
(Institutet för miljömedicin / Institute of Environmental Medicine, 2021-05-31)Background: Previous studies suggest worse leukaemia survival for children with siblings, but the evidence is sparse, inconsistent and does not consider clinical factors. We explored the associations between number of ... -
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2021-03-05)Background: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated ... -
Effects of inhaled corticosteroids on DNA methylation in peripheral blood cells in children with asthma
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2019-09-25) -
Cesarean delivery, preterm birth and risk of food allergy : nationwide Swedish cohort study of over 1 million children
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2019-08-06)Background & Objectives: Little is known about early life risk factors for food allergy in children. We examined the association between perinatal characteristics and future risk of food allergy in offspring. Methods: ... -
Bidirectional relationship between eating disorders and autoimmune diseases
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2018-11-26)Background: Immune system dysfunction may be associated with eating disorders, and associations could have implications for detection, risk assessment, and treatment of both autoimmune diseases and eating disorders. However, ... -
Are carriers of CYP21A2 mutations less vulnerable to psychological stress? A population-based national cohort study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-06-14)Background: Congenital adrenal hyperplasia (CAH) is one of the most common monogenic autosomal recessive disorders with an incidence of one in 15 000. About one in 70 individuals in the general population are carriers of ... -
Increased cardiovascular and metabolic morbidity in patients with 21-hydroxylase deficiency : a Swedish population-based national cohort study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-29)CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. OBJECTIVE: ... -
Registers of the Swedish total population and their use in medical research
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-28)The primary aim of the Swedish national population registration system is to obtain data that (1) reflect the composition, relationship and identities of the Swedish population and (2) can be used as the basis for correct ... -
Hypospadias as a novel feature in spinal bulbar muscle atrophy
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-27)Spinal and bulbar muscle atrophy (SBMA) is an X-linked neuromuscular disorder caused by CAG repeat expansions in the androgen receptor (AR) gene. The SBMA phenotype consists of slowly progressive neuromuscular symptoms and ... -
Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-20)Context: Reports on mortality in patients with congenital adrenal hyperplasia (CAH) are lacking. Objective: To study mortality and causes of death in CAH. Design, Setting and Participants: We studied patients ... -
Exposure to air pollution from traffic and neurodevelopmental disorders in Swedish twins
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-03-17)Background: Recent studies have reported associations between air pollution exposure and neurodevelopmental disorders in children but the role of pre- and postnatal exposure has not been elucidated. Aim: We aimed ... -
The observed association between maternal anxiety and adolescent asthma : children of twin design suggest familial effects
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2017-01-02)BACKGROUND: Previous studies indicate that maternal anxiety is associated with asthma in the adolescent child, but mechanisms are unclear. OBJECTIVE: To investigate the association between maternal anxiety and ... -
Exploring women's fear of childbirth in a high maternal mortality setting on the Arabian Peninsula
(Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2016-06-29)Background: Few studies from low-income countries have addressed women's fear of childbirth (FOC) although likely to affect women during both pregnancy and childbirth. The aim of this study was to explore FOC in a high ... -
Prolonged second stage of labor is associated with low Apgar score
(Inst för medicin, Solna / Dept of Medicine, Solna, 2015-11-09)There is no consensus on the effects of a prolonged second stage of labor on neonatal outcomes. In this large Swedish population-based cohort study, our objective was to investigate prolonged second stage and risk of low ... -
Breastfeeding, asthma, and allergy : a tale of two cities
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2015-07-21)BACKGROUND: The effect of breastfeeding duration on subsequent asthma and allergy remains the subject of much controversy. OBJECTIVE: To investigate whether differences in study design or disease-related exposure ... -
Hypospadias and increased risk for neurodevelopmental disorders
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-07-31)BACKGROUND: Hypospadias (aberrant opening of the urethra on the underside of the penis) occurs in 1 per 300 newborn boys. It has been previously unknown whether this common malformation is associated with increased psychiatric ... -
The roots of autism and ADHD twin study in Sweden (RATSS)
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-25)Neurodevelopmental disorders affect a substantial minority of the general population. Their origins are still largely unknown, but a complex interplay of genetic and environmental factors causing disturbances of the central ...