Deliberate self-harm among adolescents : course, outcome and treatment
Author: Ohlis, Anna
Date: 2020-12-11
Location: Konferenslokal Tor, plan 10, Solnavägen 4, Torsplan, Stockholm
Time: 13.00
Department: Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience
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Thesis (1.034Mb)
Abstract
Background: Self-harm among adolescents is prevalent, and is a risk factor for suicide, which is one of the leading causes of death among youth worldwide. There is a need to better understand the role and impact of self-harm within clinical samples, and the subsequent risks associated with self-harm with and without suicidal intent. Dialectical behavior therapy (DBT) has the strongest empirical support for treatment of self-harm among adolescents, and extended knowledge on important treatment components is critical for the development of brief, efficacious interventions that are easily accessible for adolescents.
Aim: The aims were to study clinical and psychosocial correlates as well as long-term outcome among clinical samples with self-harm and explore experiences of care among young adults who have participated in specialist-level interventions targeting self-harm (i.e. DBT).
Methods: The clinical and psychosocial correlations was studied in a case-control study (N = 25,161) comparing three subgroups of patients; 1) self-harm only, 2) self-harm and suicidality, and 3) neither self-harm nor suicidality (controls). Linear regression and logistic regression were used to calculate associations. Outcomes were studied in three different longitudinal cohort studies: 1) outcomes after self-harm with and without suicidal ideation/behavior (N = 6,120), 2) outcomes for boys or girls with self-harm (N = 110,072), and 3) outcomes after nonsuicidal self-injury (NSSI) or suicide attempt (SA) using NSSI and SA as time-varying covariates (N = 2,219). By using Cox regression, Hazard Ratios with 95% Confidence Intervals were estimated for each outcome. Salient treatment components were studied with a qualitative analysis of 19 semi-structured interviews with former DBT patients.
Results: Self-harm within clinical populations was associated with higher clinical and psychosocial burden and higher risk of adverse outcomes, e.g. alcohol/substance misuse, violent and nonviolent criminality, as compared with patients with no self-harm. Patients with both self-harm and suicidality are the most vulnerable group. The young self-harming patient valued a therapist who showed explicit concern and trust in the patient’s competence to change destructive behaviors, but also meeting and learning from peers.
Conclusion: Help-seeking boys and girls with self-harm need appropriate care and assessment, including prevention and treatment of alcohol and substance use. Self-harm might serve as a risk marker for emotion dysregulation and impulsivity within both sexes. Suicidality in addition to self-harm need to be regularly assessed and signals highly increased risks for future adverse outcomes. Interventions that lower the risks are necessary. Young patients with self-harm, can be strongly motivated, and work hard, to improve their well- being and pursue a life worth living. Teaching and learning from peers might be of particular value and importance among adolescents.
Aim: The aims were to study clinical and psychosocial correlates as well as long-term outcome among clinical samples with self-harm and explore experiences of care among young adults who have participated in specialist-level interventions targeting self-harm (i.e. DBT).
Methods: The clinical and psychosocial correlations was studied in a case-control study (N = 25,161) comparing three subgroups of patients; 1) self-harm only, 2) self-harm and suicidality, and 3) neither self-harm nor suicidality (controls). Linear regression and logistic regression were used to calculate associations. Outcomes were studied in three different longitudinal cohort studies: 1) outcomes after self-harm with and without suicidal ideation/behavior (N = 6,120), 2) outcomes for boys or girls with self-harm (N = 110,072), and 3) outcomes after nonsuicidal self-injury (NSSI) or suicide attempt (SA) using NSSI and SA as time-varying covariates (N = 2,219). By using Cox regression, Hazard Ratios with 95% Confidence Intervals were estimated for each outcome. Salient treatment components were studied with a qualitative analysis of 19 semi-structured interviews with former DBT patients.
Results: Self-harm within clinical populations was associated with higher clinical and psychosocial burden and higher risk of adverse outcomes, e.g. alcohol/substance misuse, violent and nonviolent criminality, as compared with patients with no self-harm. Patients with both self-harm and suicidality are the most vulnerable group. The young self-harming patient valued a therapist who showed explicit concern and trust in the patient’s competence to change destructive behaviors, but also meeting and learning from peers.
Conclusion: Help-seeking boys and girls with self-harm need appropriate care and assessment, including prevention and treatment of alcohol and substance use. Self-harm might serve as a risk marker for emotion dysregulation and impulsivity within both sexes. Suicidality in addition to self-harm need to be regularly assessed and signals highly increased risks for future adverse outcomes. Interventions that lower the risks are necessary. Young patients with self-harm, can be strongly motivated, and work hard, to improve their well- being and pursue a life worth living. Teaching and learning from peers might be of particular value and importance among adolescents.
List of papers:
I. Bjureberg, J., Ohlis, A., Ljótsson, B., D’Onofrio, B. M., Hedman-Lagerlöf, E., Jokinen, J., Sahlin, H., Lichtenstein, P., Cederlöf, M., Hellner, C. (2019). Adolescent self-harm with and without suicidal ideation and behaviors: Cross-sectional and longitudinal analyses of a Swedish regional register. Journal of Child Psychology and Psychiatry. 60(3), 295-30.
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II. Ohlis, A., Bjureberg, J., Lichtenstein, P., D’Onofrio, B. M., Fruzzetti, A. E., Cederlöf, M., Hellner, C. (2020). Comparison of suicide risk and other outcomes among boys and girls who self-harm. European Child & Adolescent Psychiatry. 2020 Dec; 29(12):1741-1746.
Fulltext (DOI)
Pubmed
View record in Web of Science®
III. Bjureberg, J., Kuja-Halkola, R., Ohlis, A., Lichtenstein, P., D’Onofrio, B. M., Hellner, C., Cederlöf, M. Adverse clinical outcomes in adolescents with clinician-rated nonsuicidal self-injury and suicide attempt: Longitudinal cohort study. [Manuscript]
IV. Ohlis, A., Bjureberg, J., Simonsson, O., Kerj, E., Hallek, C., Fruzzetti, A. E., Cederlöf, M., Hellner, C. Helpful approached from the DBT-A patient’s perspective: A qualitative analysis of former patients’ experiences. [Manuscript]
I. Bjureberg, J., Ohlis, A., Ljótsson, B., D’Onofrio, B. M., Hedman-Lagerlöf, E., Jokinen, J., Sahlin, H., Lichtenstein, P., Cederlöf, M., Hellner, C. (2019). Adolescent self-harm with and without suicidal ideation and behaviors: Cross-sectional and longitudinal analyses of a Swedish regional register. Journal of Child Psychology and Psychiatry. 60(3), 295-30.
Fulltext (DOI)
Pubmed
View record in Web of Science®
II. Ohlis, A., Bjureberg, J., Lichtenstein, P., D’Onofrio, B. M., Fruzzetti, A. E., Cederlöf, M., Hellner, C. (2020). Comparison of suicide risk and other outcomes among boys and girls who self-harm. European Child & Adolescent Psychiatry. 2020 Dec; 29(12):1741-1746.
Fulltext (DOI)
Pubmed
View record in Web of Science®
III. Bjureberg, J., Kuja-Halkola, R., Ohlis, A., Lichtenstein, P., D’Onofrio, B. M., Hellner, C., Cederlöf, M. Adverse clinical outcomes in adolescents with clinician-rated nonsuicidal self-injury and suicide attempt: Longitudinal cohort study. [Manuscript]
IV. Ohlis, A., Bjureberg, J., Simonsson, O., Kerj, E., Hallek, C., Fruzzetti, A. E., Cederlöf, M., Hellner, C. Helpful approached from the DBT-A patient’s perspective: A qualitative analysis of former patients’ experiences. [Manuscript]
Institution: Karolinska Institutet
Supervisor: Hellner, Clara
Co-supervisor: Bjureberg, Johan; Fruzzetti, Alan; Lichtenstein, Paul
Issue date: 2020-11-20
Rights:
Publication year: 2020
ISBN: 978-91-8016-004-9
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