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  • Contrast-enhanced ultrasound is useful for the evaluation of focal liver lesions in children 

    Torres, Alvaro; Koskinen, Seppo K; Gjertsen, Henrik; Fischler, Björn (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-28)
    Introduction: Contrast-enhanced ultrasound (CEUS) is a widely used diagnostic method. In adults, it has been proven to be a useful alternative to CT and MRI for the characterisation of focal liver lesions (FLLs). However, ...
  • Contrast-enhanced ultrasound for identifying circulatory complications after liver transplants in children 

    Torres, Alvaro; Koskinen, Seppo K; Gjertsen, Henrik; Fischler, Björn (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-28)
    Our main goal with this study was to share our off-label experience with CEUS for identifying circulatory complications after liver transplantation in children. A total of 74 CEUS examinations performed on 34 pediatric ...
  • Contrast-enhanced ultrasound using sulfur hexafluoride is safe in the pediatric setting 

    Torres, Alvaro; Koskinen, Seppo K; Gjertsen, Henrik; Fischler, Björn (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2022-03-28)
    Background: Contrast-enhanced ultrasound (CEUS) by using sulfur hexafluoride microbubbles is not licensed for use in children, but its off-label use is widespread. Purpose: To outline our experience with the off-label ...
  • Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5 

    Golembiewska, Edyta; Qureshi, Abdul Rashid; Dai, Lu; Lindholm, Bengt; Heimbürger, Olof; Söderberg, Magnus; Brismar, Torkel B; Ripsweden, Jonaz; Barany, Peter; Johnson, Richard J; Stenvinkel, Peter (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-03-05)
    Background: Vascular calcification (VC) is an independent predictor of cardiovascular disease (CVD) present in 30– 70% of patients with chronic kidney disease (CKD). Copeptin is a sensitive surrogate marker of arginine ...
  • Early vascular ageing and cellular senescence in chronic kidney disease 

    Dai, Lu; Qureshi, Abdul Rashid; Witasp, Anna; Lindholm, Bengt; Stenvinkel, Peter (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-03-05)
    Chronic kidney disease (CKD) is a clinical model of premature ageing characterized by progressive vascular dis- ease, systemic inflammation, muscle wasting and frailty. The predominant early vascular ageing (EVA) process ...
  • Circulating proteins as predictors of cardiovascular mortality in endstage renal disease 

    Feldreich, Tobias; Nowak, Christoph; Fall, Tove; Carlsson, Axel C; Carrero, Juan-Jesus; Ripsweden, Jonaz; Qureshi, Abdul Rashid; Heimbürger, Olof; Barany, Peter; Stenvinkel, Peter; Vuilleumier, Nicolas; Kalra, Philip A; Green, Darren; Ärnlöf, Johan (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2021-02-24)
    Introduction: Proteomic profiling of end-stage renal disease (ESRD) patients could lead to improved risk prediction and novel insights into cardiovascular disease mechanisms. Plasma levels of 92 cardiovascular disease-associated ...
  • Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization 

    Karlöf, Eva; Seime, Till; Dias, Nuno; Lengqvist, Mariette; Witasp, Anna; Almqvist, Håkan; Kronqvist, Malin; Gådin, Jesper Robert; Odeberg, Jacob; Maegdefessel, Lars; Stenvinkel, Peter; Matic, Ljubica Perisic; Hedin, Ulf (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2021-02-24)
    Background and aims: Unstable carotid atherosclerosis causes stroke, but methods to identify patients and lesions at risk are lacking. We recently found enrichment of genes associated with calcification in carotid plaques ...
  • Risk of hospitalization and death due to bone fractures after breast cancer: a registry-based cohort study 

    Colzani, Edoardo; Clements, Mark; Johansson, Anna L V; Liljegren, Annelie; He, Wei; Brand, Judith S; Adolfsson, Jan; Fornander, Tommy; Hall, Per; Czene, Kamila (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2016-12-01)
    BACKGROUND: Bone fractures may have an impact on prognosis of breast cancer. The long-term risks of bone fracture in breast cancer patients have not been thoroughly studied. METHODS: Poisson regression was used to ...
  • Smoking, smoking cessation and fracture risk in elderly women followed for 10 years 

    Thorin, Mats H; Wihlborg, Axel; Åkesson, Kristina; Gerdhem, Paul (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2015-09-07)
    Summary: This study examines the impact of smoking and smoking cessation on fracture risk in 75-year-old women followed for 10 years. Smoking increased fracture risk, especially for vertebral fractures. Smoking cessation ...
  • Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis 

    Grauers, Anna; Wang, Jingwen; Einarsdottir, Elisabet; Simony, Ane; Danielsson, Aina; Åkesson, Kristina; Ohlin, Acke; Halldin, Klas; Grabowski, Pawel; Tenne, Max; Laivuori, Hanne; Dahlman, Ingrid; Andersson, Mikkel; Bach Christensen, Steen; Karlsson, Magnus K; Jiao, Hong; Kere, Juha; Gerdhem, Paul (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2015-08-05)
    Background: Idiopathic scoliosis is a spinal deformity affecting approximately 3% of otherwise healthy children or adolescents. The etiology is still largely unknown but has an important genetic component. Genome-wide ...
  • An observational study on the outcome after surgery for lumbar disc herniation in adolescents compared to adults based on the Swedish Spine Register 

    Lagerbäck, Tobias; Elkan, Peter; Möller, Hans; Grauers, Anna; Diarbakerli, Elias; Gerdhem, Paul (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2015-08-05)
    BACKGROUND CONTEXT: Disc-related sciatica has a prevalence of about 2% in adults, but is rare in adolescents. If conservative treatment is unsuccessful, surgery is an option. PURPOSE: The aim of this study was to ...
  • Language and mathematical problems as precursors of psychotic-like experiences and juvenile mania symptoms 

    Cederlöf, Martin; Östberg, Per; Pettersson, Erik; Anckarsäter, Henrik; Hellner Gumpert, Clara; Lundström, Sebastian; Lichtenstein, Paul (Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2014-06-25)
    BACKGROUND: Psychotic-like experiences (PLEs) and juvenile mania in adolescence index risk for severe psychopathology in adulthood. The importance of childhood problems with communication, reading, speech and mathematics ...
  • Development of classical Hodgkin’s lymphoma in an adult with biallelic STXBP2 mutations 

    Machaczka, Maciej; Klimkowska, Monika; Chiang, Samuel C C; Meeths, Marie; Müller, Martha-Lena; Gustafsson, Britt; Henter, Jan-Inge; Bryceson, Yenan T (Inst för medicin, Huddinge / Dept of Medicine, Huddinge, 2013-07-31)
    Experimental model systems have delineated an important role for cytotoxic lymphocytes in the immunosurveillance of cancer. In humans, perforin-deficiency has been associated with occurrence of hematologic malignancies. ...
  • Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes 

    Gyllenberg, Alexandra; Asad, Samina; Piehl, Fredrik; Swanberg, Maria; Padyukov, Leonid; van Yserloo, Brian; Graham, Jinko; Rutledge, Elizabeth; Orho-Melander, Marju; Lindholm, Eero; Graff, Caroline; Forsell, Charlotte; Åkesson, Karin; Landin-Olsson, Mona; Carlsson, Annelie; Forsander, Gun; Ivarsson, Sten; Larsson, Helena; Alfredsson, Lars; Åkesson, Kristina; Olsson, Tomas; Kockum, Ingrid; Lindblad, Bengt; Ludvigsson, Johnny; Marcus, Claude; Lernmark, Åke; McNeney, Brad; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group; Better Diabetes Diagnosis Study Group (Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2013-03-25)
    The major histocompatibility complex class II transactivator (CIITA) gene (16p13) has been reported to associate with susceptibility to multiple sclerosis, rheumatoid arthritis and myocardial infarction, recently also to ...
  • Disseminating evidence from health technology assessment : the case of tobacco prevention 

    Axelsson, Susanna; Helgason, Asgeir R; Lund, Karl E; Adolfsson, Jan (Inst för folkhälsovetenskap / Dept of Public Health Sciences, 2012-08-24)
    OBJECTIVES: The aims of the present study were to investigate the awareness among dentists and dental hygienists of evidence-based reports and guidelines on tobacco cessation activities and the impact these publications ...
  • Hospital incident command system (HICS) performance in Iran : decision making during disasters 

    Djalali, Ahmadreza; Castrén, Maaret; Hosseinijenab, Vahid; Khatib, Mahmoud; Ohlen, Gunnar; Kurland, Lisa (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2012-05-25)
    Background: Hospitals are cornerstones for health care in a community and must continue to function in the face of a disaster. The Hospital Incident Command System (HICS) is a method by which the hospital operates when an ...
  • A fundamental, national, medical disaster management plan : an education-based model 

    Djalali, Ahmadreza; Hosseinijenab, Vahid; Hasani, Azadeh; Shirmardi, Kianoush; Castrén, Maaret; Öhlén, Gunnar; Panahi, Farzad (Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2012-05-25)
    During disasters, especially earthquakes, health systems are expected to play an essential role in reducing mortality and morbidity. The most significant naturally occurring disaster in Iran is earthquakes; they have killed ...
  • Facilitators and obstacles in pre-hospital medical response to earthquakes : a qualitative study 

    Djalali, Ahmadreza; Khankeh, Hamidreza; Öhlén, Gunnar; Castrén, Maaret; Kurland, Lisa (Inst för klinisk vetenskap, intervention och teknik / Dept of Clinical Science, Intervention and Technology, 2012-03-28)
    BACKGROUND: Earthquakes are renowned as being amongst the most dangerous and destructive types of natural disasters. Iran, a developing country in Asia, is prone to earthquakes and is ranked as one of the most vulnerable ...