Artiklar / Articles: Recent submissions
Now showing items 21-40 of 401
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Temporal trends in adverse pregnancy outcomes in axial spondyloarthritis in Sweden : a cohort study
(Inst för medicin, Solna / Dept of Medicine, Solna, 2023-06-30)Background: Evidence on the risks associated with pregnancy and childbirth in women with axial spondyloarthritis is scarce and conflicting, with more research needed to guide policy and clinical practice. We aimed to assess ... -
Dementia and psychotropic medications are associated with significantly higher mortality in geriatric patients hospitalized with COVID-19 : data from the StockholmGeroCovid project
(Inst för neurobiologi, vårdvetenskap och samhälle / Dept of Neurobiology, Care Sciences and Society, 2023-02-27)Background: Dementia and psychotropic medications are discussed as risk factors for severe/lethal outcome of the coronavirus disease 2019 (COVID-19). We aimed to explore the associations between the presence of dementia ... -
Allergies to food and airborne allergens in children and adolescents : role of epigenetics in a changing environment
(Inst för klinisk forskning och utbildning, Södersjukhuset / Dept of Clinical Science and Education, Södersjukhuset, 2023-02-17)Allergic diseases today affect millions of children and adolescents worldwide. In this review, we focus on allergies to food and airborne allergens, and provide examples of prevalence trends during a time when climate ... -
"You have to know why you're doing this" : a mixed methods study of the benefits and burdens of self-tracking in Parkinson's disease
(Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2023-02-17)Background: This study explores opinions and experiences of people with Parkinson's disease (PwP) in Sweden of using self-tracking. Parkinson's disease (PD) is a neurodegenerative condition entailing varied and changing ... -
Meeting the burden of self-management : qualitative study investigating the empowering behaviors of patients and informal caregivers
(Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2023-02-16)Background: Patient empowerment is an important concept and a movement toward person-centered care of patients with chronic conditions. Nevertheless, to date, most research on empowered patients or informal caregivers has ... -
From information seekers to innovators : qualitative analysis describing experiences of the second generation of e-patients
(Inst för lärande, informatik, management och etik / Dept of Learning, Informatics, Management and Ethics, 2023-02-15)Background: Current health care systems are rarely designed to meet the needs of people living with chronic conditions. However, some patients and informal caregivers are not waiting for the health care system to redesign ... -
Maternal asthma and early fetal growth : the MAESTRO study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-02-08)Background: Several maternal conditions can affect fetal growth, and asthma during pregnancy is known to be associated with lower birth weight and shorter gestational age. Objective: In a new Swedish cohort study ... -
Paediatric asthma and non-allergic comorbidities : a review of current risk and proposed mechanisms
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-24)It is increasingly recognized that children with asthma are at a higher risk of other non-allergic concurrent diseases than the non-asthma population. A plethora of recent research has reported on these comorbidities and ... -
Season of birth, childhood asthma and allergy in a nationwide cohort : mediation through lower respiratory infections
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-23)Background: Previous studies have suggested an association between season of birth and risk of childhood asthma and allergic disease. The association may be modified by birth year and region, or mediated by respiratory ... -
Risk and predictors of out-of-home care placement among children and adolescents with parental mental illness : a population-based cohort study in Sweden (Study IV)
(Inst för global folkhälsa / Dept of Global Public Health, 2023-01-17)Here, we propose a nationwide population-based study on predictors of out-of-home care placement among children of mentally ill parents, using rich information from Swedish national health and administrative registers. We ... -
Understanding the relationship between asthma and autism spectrum disorder : a population-based family and twin study
(Inst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and Biostatistics, 2023-01-17)Background: There is some evidence that autism spectrum disorder (ASD) frequently co-occurs with immune-mediated conditions including asthma. We aimed to explore the familial co-aggregation of ASD and asthma using different ... -
Limited association between markers of stress during pregnancy and fetal growth in 'Born into Life' : a new prospective birth cohort
(Institutet för miljömedicin / Institute of Environmental MedicineInst för medicinsk epidemiologi och biostatistik / Dept of Medical Epidemiology and BiostatisticsInst för kliniska vetenskaper, Danderyds sjukhus / Dept of Clinical Sciences, Danderyd Hospital, 2023-01-17)Aims: We aimed to investigate the associations between perceived maternal stress or salivary cortisol levels during pregnancy and birthweight. Methods: In 2010-2012, we recruited 92 women living in Stockholm, Sweden, ... -
Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles
(Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2022-12-06)Extracellular vesicles (EVs) can be functionalized to display specific protein receptors on their surface. However, surface-display technology typically labels only a small fraction of the EV population. Here, we show that ... -
Visuo-thermal congruency modulates the sense of body ownership
(Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)Thermosensation has been redefined as an interoceptive modality that provides information about the homeostatic state of the body. However, the contribution of thermosensory signals to the sense of body ownership remains ... -
Limits of cross-modal plasticity? Short-term visual deprivation does not enhance cardiac interoception, thermosensation, or tactile spatial acuity
(Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)In the present study, we investigated the effect of short-term visual deprivation on discriminative touch, cardiac interoception, and thermosensation by asking 64 healthy volunteers to perform four behavioral tasks. The ... -
Editorial : When the body feels like mine : constructing and deconstructing the sense of body ownership through the lifespan
(Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08) -
Interoception as independent cardiac, thermosensory, nociceptive, and affective touch perceptual submodalities
(Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)Interoception includes signals from inner organs and thin afferents in the skin, providing information about the body’s physiological state. However, the functional relationships between interoceptive submodalities are ... -
The role of the skin in interoception : a neglected organ?
(Inst för neurovetenskap / Dept of Neuroscience, 2022-09-08)In the past two decades, interoception has received increasing attention in the fields of psychology and cognitive science, as well as neuroscience and physiology. A plethora of studies adopted the perception of cardiac ... -
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function
(Inst för onkologi-patologi / Dept of Oncology-Pathology, 2022-08-19)Oxidative DNA damage is recognised by 8-oxoguanine (8-oxoG) DNA glycosylase 1 (OGG1), which excises 8-oxoG, leaving a substrate for apurinic endonuclease 1 (APE1), initiating repair. Here, we describe a small molecule ... -
Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure
(Inst för cell- och molekylärbiologi / Dept of Cell and Molecular Biology, 2022-08-19)The dysregulated physical interaction between two intracellular membrane proteins, the sarco/endoplasmic reticulum Ca2+ ATPase and its reversible inhibitor phospholamban, induces heart failure by inhibiting calcium cycling. ...